Aspergillary bronchopneumonia

an unusual cause of atelectasis and asphyxia in a leukemic patient

Authors

  • Elvira Deolinda Rodrigues Pereira Velloso Universidade de São Paulo
  • Gracia Aparecida Martinez Universidade de São Paulo
  • Pedro Enrique Dorlhiac-Llacer Universidade de São Paulo
  • Dalton Alencar Fischer Chamone Universidade de São Paulo

Keywords:

aspergillosis, atelectasis, leukemia

Abstract

A 22-year-old man in his first relapse of T-acute lymphoblastic leukemia developed fever and a pulmonary infiltrate after 23 days of granulocytopenia. Although having been under amphotericin B for 10 days, productive purulent cough ensued, with right lobe atelectasis and acute ventilatory failure that resolved after the elimination of a thick gelatinous bronchial plug. Sputum cultures yielded Candida Albicans and Staphylococcus epidermidis, and microscopic examination of the sputum plug disclosed Aspergillus hyphae. The patient died 9 days after, of a disseminated Aspergillus infection, confirmed by necropsy.

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Author Biographies

Elvira Deolinda Rodrigues Pereira Velloso, Universidade de São Paulo

Brazil Fundação Pró-Sangue/Hemocentro of São Paulo, General Clinical Hospital Medical School of São Paulo University, Department of Hematology, São Paulo, Brazil.

Gracia Aparecida Martinez, Universidade de São Paulo

Brazil Fundação Pró-Sangue/Hemocentro of São Paulo, General Clinical Hospital Medical School of São Paulo University, Department of Hematology, São Paulo, Brazil.

Pedro Enrique Dorlhiac-Llacer, Universidade de São Paulo

Brazil Fundação Pró-Sangue/Hemocentro of São Paulo, General Clinical Hospital Medical School of São Paulo University, Department of Hematology, São Paulo, Brazil.

Dalton Alencar Fischer Chamone, Universidade de São Paulo

Brazil Fundação Pró-Sangue/Hemocentro of São Paulo, General Clinical Hospital Medical School of São Paulo University, Department of Hematology, São Paulo, Brazil.

References

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LEVINE A.S.; GRAW R.G. & YONG R.C.- Management of infections in patients with leukemia and lymphoma: current concepts and experimental approaches. Sem Hematol 9:141-178, 1972.

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ORR D.P.; MYEROWITZ R.L.& DUBOIS P.J.- Pathoradiologic correlation of invasive pulmonary aspergillosis in the compromised host. Cancer 41:2028-2039, 1978.

SARAL R.- Candida and aspergillus infections in immunocompromised patients: an overview. Rev Inf Dis 13:487-492, 1991.

YOUNG R.C.; BENNETT J.E.; VOGEL C.L.; CARBONE P.P.& DE VITA V.T.- Aspergillosis:the spectrum of the disease in 98 patients. Medicine 49:147-73, 1970.

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Published

1994-10-10

How to Cite

1.
Velloso EDRP, Martinez GA, Dorlhiac-Llacer PE, Chamone DAF. Aspergillary bronchopneumonia: an unusual cause of atelectasis and asphyxia in a leukemic patient. Sao Paulo Med J [Internet]. 1994 Oct. 10 [cited 2025 Jun. 14];112(4):639-41. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/1487

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Section

Original Article