NFκB inhibitors as a potential novel hypothesized treatment for psoriasis

Namazi MR. Steroid sulfatase inhibitors as novel additions to the antipsoriatic armamentarium. Med Sci Monit. 2005;11(3):HY7-9.

Abdou AG, Hanout HM. Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study. J Cutan Pathol. 2008;35(5):445-51.

Bowcock AM. The genetics of psoriasis and autoimmunity. Annu Rev Genomics Hum Genet. 2005;6:93-122.

Tsuruta D. NF-kappaB links keratinocytes and lymphocytes in the pathogenesis of psoriasis. Recent Pat Inflamm Allergy Drug Discov. 2009;3(1):40-8.

Doger FK, Dikicioglu E, Ergin F et al. Nature of cell kinetics in psoriatic epidermis. J Cutan Pathol. 2007;34(3):257-63.

Lizzul PF, Aphale A, Malaviya R, et al. Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept. J Invest Dermatol. 2005;124(6):1275-83.

Zhang M, Zhu L, Feng Y, et al. Effects of acitretin on proliferative inhibition and RANTES production of HaCaT cells. Arch Dermatol Res. 2008;300(10):575-81.

Mrowietz U, Asadullah K. Dimethylfumarate for psoriasis: more than a dietary curiosity. Trends Mol Med. 2005;11(1):43-8.

Maioli E, Valacchi G. Rottlerin: bases for a possible usage in psoriasis. Curr Drug Metab. 2010;11(5):425-30.

Lories RJ, Derese I, Luyten FP, de Vlam K. Activation of nuclear factor kappa B and mitogen activated protein kinases in psoriatic arthritis before and after etanercept treatment. Clin Exp Rheumatol. 2008;26(1):96-102.

Wang H, Syrovets T, Kess D, et al. Targeting NF-kappa B with a natural triterpenoid alleviates skin inflammation in a mouse model of psoriasis. J Immunol. 2009;183(7):4755-63.

Schmidt KN, Podda M, Packer L, Baeuerle PA. Anti-psoriatic drug anthralin activates transcription factor NF-kappa B in murine keratinocytes. J Immunol. 1996;156(11):4514-9.

Marchetti S, Gamas P, Belhacène N, et al. The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice. EMBO J. 2009;28(16):2449-60.

Seitz CS, Lin Q, Deng H, Khavari PA. Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proc Natl Acad Sci USA. 1998;95(5):2307-12.

Aragane Y, Yamada H, Schwarz A, et al. Transforming growth factor- alpha induces interleukin-6 in the human keratinocyte cell line HaCaT mainly by transcriptional activation. J Invest Dermatol. 1996;106(6):1192-7.

Kwon YW, Jang ER, Lee YM, et al. Insulin-like growth factor II induces interleukin-6 expression via NFkappaB activation in psoriasis. Biochem Biophys Res Commun. 2000;278(2):312-7.