Reparation of peripheral nerves with fibrin glue prepared from snake venom

preliminary results

Authors

  • Fabio Cardoso Juan Universidade do Estado de São Paulo
  • Izolete Aparecida Thomazini Universidade do Estado de São Paulo
  • Maria José Mendes Gianini Universidade do Estado de São Paulo
  • Fausto Viterbo Universidade do Estado de São Paulo
  • Elaine Toscano Universidade do Estado de São Paulo
  • Rosângela Aparecida Moraes Universidade do Estado de São Paulo

Keywords:

Fibrin glue, Snake venom, Peripheral nerves, Rats

Abstract

A new fibrin glue obtained from snake venom is presented, with possible utilization in various fields of medicine. The preparation procedures and tests in the reparation of peripheral nerves are described. The preliminary results were similar to the conventional fibrin glue procedure.

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Author Biographies

Fabio Cardoso Juan, Universidade do Estado de São Paulo

Universidade Estadual Paulista, São Paulo, São Paulo, Brazil.

Izolete Aparecida Thomazini, Universidade do Estado de São Paulo

Universidade Estadual Paulista, São Paulo, São Paulo, Brazil.

Maria José Mendes Gianini, Universidade do Estado de São Paulo

Universidade Estadual Paulista, São Paulo, São Paulo, Brazil.

Fausto Viterbo, Universidade do Estado de São Paulo

Universidade Estadual Paulista, São Paulo, São Paulo, Brazil.

Elaine Toscano, Universidade do Estado de São Paulo

Universidade Estadual Paulista, São Paulo, São Paulo, Brazil.

Rosângela Aparecida Moraes, Universidade do Estado de São Paulo

Universidade Estadual Paulista, São Paulo, São Paulo, Brazil.

References

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BARRABIN, H.; MARTIARENA, J.L.; VIDAL, J.C. & BARRIO, A. - Isolation and characterization of gyroxin from Crotalus durissus terrificus venom. In: ROSENBERG, P. Toxins: Animals, plant and microbial New York. Pergamon Press, 1978, p. 133.

BAKER, J.W.; SPOTNITZ, W.D.; MATTHEW, T.L. & NOLAN. S.P. - Successful use of fibrin glue during 2 years of surgery at a University Medical Center. Am Surg 55(3):166, 1989.

BORST, H.G.; HAUERICH, A.; WALTERBUSH, G.; MAATZ, W. & MESSNER. B. - Fibrin adhesive: An important hemostatic adjunct in cardiovascular operations: J. Thorac. Cardiovasc. Surg. 84:548, 1982.

KLETHER. G. - Comparative evaluation of conventionally sutured and clot-sutured microsurgical anastomosis. In: SCHEIEDER, P. Microsurgery for stroke New York, Springer-Verlag, (Ch, 19).

LOWEY, O. H.; ROSEBROUGH, N.J.; FARR, A.L. & RANDALI, R.J. - Protein measurement with the folin phenol reagent. I Biol Chem 193:265-275, 1951.

LUPINETTI, F.M.; STONY, W.S.; ALFORD Jr, W.C.; BUJRMS, G.R.; CLASSFORD, Jr, D.M.; PETRACECK, M.R. & THOMAS, C.S. - Cryoprecipitate-topical Trombin Glue. Initial experience in patients undergoing cardiac operations. J. Thorac Cardio-vasc. Surg. 90:502, 1985.

MARLAND, F.S. & PIRKLE, H. - Biological activities and biochemical properties of thrombin-like enzymes from snake venoms. In: LUNDBLAD, R.L; ENTON, J.W; MANM, K.G; Chem and Biol of Trombin. Ann Arbor Science Ann Arbor, Michigan, 1977, p 71.

WALKER, R.H. - Blood and blood components: preparation, storage and shipment. In: Technical Manual of American Association of blood banks (A.A.B.B.), Ch 3, 10 ed., 1990, p. 47.

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Published

1995-09-09

How to Cite

1.
Juan FC, Thomazini IA, Gianini MJM, Viterbo F, Toscano E, Moraes RA. Reparation of peripheral nerves with fibrin glue prepared from snake venom: preliminary results. Sao Paulo Med J [Internet]. 1995 Sep. 9 [cited 2026 Sep. 21];113(5):1000-2. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/1741

Issue

Vol. 113 No. 5 (1995)

Section

Short Communication

License

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This work is licensed under a Creative Commons Attribution 4.0 International License.