Effects of simple hysterectomy on bone loss

Authors

  • Rosana Durães Simões Escola Paulista de Medicina
  • Edmund Chada Baracat Escola Paulista de Medicina
  • Vera Lúcia Szjenfeld Escola Paulista de Medicina
  • Geraldo Rodrigues de Lima Escola Paulista de Medicina
  • Wagner José Gonçalves Escola Paulista de Medicina
  • Claudia de Carvalho Ramos Bortoletto Escola Paulista de Medicina

Keywords:

Premenopausal hysterectomy, Postmenopausal osteoporosis, Photon absorptiometry

Abstract

Lumbar spine and proximal femoral bone densities of Caucasian women, aged 35-45, were measured by dual photon densitometry model DPX. The measurement sites were assessed at the lumbar spine (vertebrae L2 to L4) and at the proximal femur (trochanter, femoral neck and Ward's triangle). After exclusion of women with climacteric symptoms, sterilized patients or those with menopausal concentrations of gonadotrophins, the study included 22 subjects: 11 menstruant (control group) and 11 hysterectomized. The hysterectomies were without oophorectomy and had been performed during the previous five years. The bone densities of the hysterectomized women were lower than those of the normal ones, but significantly lower at the Ward's triangle.

Downloads

Download data is not yet available.

Author Biographies

Rosana Durães Simões, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Medicine, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Gynecology and Obstetrics, São Paulo, Brazil.

Edmund Chada Baracat, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Medicine, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Gynecology and Obstetrics, São Paulo, Brazil.

Vera Lúcia Szjenfeld, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Medicine, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Gynecology and Obstetrics, São Paulo, Brazil.

Geraldo Rodrigues de Lima, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Medicine, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Gynecology and Obstetrics, São Paulo, Brazil.

Wagner José Gonçalves, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Medicine, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Gynecology and Obstetrics, São Paulo, Brazil.

Claudia de Carvalho Ramos Bortoletto, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Medicine, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Gynecology and Obstetrics, São Paulo, Brazil.

References

ALBRIGHT, F.; SMITH, P. H. & RICHARDSON, A. M. - Postmenopausal osteoporosis; its clinical features. J Am Med Assoc 116(22): 2465-74, 1940.

CANALIS,E.; THOMAS, L.M. & CENTRELLA, M. - The role of growth factors in skeletal remodeling. Endocrinol Metab Clin North Am 18(4): 903-18, 1989.

CENTERWALLE, B.S. - Premenopausal hysterectomy and cardiovascular disease. Am J Obstet Gynecol 139: 58-61, 1981.

CORSON,S.L.; LEVINSON,C.J.; BATZER,F.R. & OTIS,C. - Hormonal levels following sterilization and hysterectomy. J Reprod Med 26(7): 363-70, 1981.

HOLLANDER M & WOLFE, D.A. - Nonparametric statistical methods New York, WILEY, 1973. p. 503.

HRESHCHYSHYN, M. M.; HOPKINS, A.; ZYLSTRA, S. & ANBAR, M. - Effects of natural menopause, hysterectomy and oophorectomy in lumbar spine and femoral neck bone densities. Obstet Gynecol 72(4): 631-8, 1988.

KAISER,R.; KUSCHE,M. & WURZ,H. - Hormone levels in women after hysterectomy. Arch Gynecol Obstet 244(3): 169-73, 1989.

KOUTSILIERIS M. - Human uterus - derived growth substances for rat bone cells and fibroblasts. Am J Obstet Gynecol 161(5): 1313-17, 1989.

LINDSAY,R. - Prevention of spinal osteoporosis in oophorectomised women. Lancet 2: 1151-3, 1980.

MENON, R.K.; OKONOFUA,F.F.; AGNEW,J.E.; THOMAS, M. ; BELL,J.;O' BRIEN, P. M. S. & DANDONA,P. - Endocrine and metabolic effects of simple hysterectomy. Int J Gynaecol Obstet 25: 459-63, 1987.

RAISZ,L.B. - Local and systemic factors in the pathogenesis of osteoporosis. N Engl J Med 318(23): 818-27, 1988.

RIEDEL, H.H.; LEHMANN-WILLENBROCK.E. & SEMM,K. - Ovarian failure phenomenon after hysterectomy. J Reprod Med 32(7):597-600,1986.

SIDDLE,N.; SARREL,P. & WHITEHEAD,M. - The effect of hysterectomy on the age of ovarian failure: identification of a subgroup of women with premature loss of ovarian function and literature review. Fertil Steril 47(1): 94-100, 1987.

SIEGEL,S. - Estatistica no parametrica aplicada a las ciencias de la conduta 2. ed. Mexico, TriIlas, 1975. 346p.

SPECTOR,T.D. & HUSKISSON,E.C. - A rational approach to the prevention and treatment of postmenopausal osteoporosis. Drugs 37(2): 205-11, 1989.

ZECCHI de SOUZA,A.; FONSECA,A.M.; IZZO, V. M. ; CLAUZET, R. M. & SALVATORE, C. A. - Ovarian histology and function after total abdominal hysterectomy. Obstet Gynecol 68(6):847-9, 1986.

Downloads

Published

1995-11-11

How to Cite

1.
Simões RD, Baracat EC, Szjenfeld VL, Lima GR de, Gonçalves WJ, Bortoletto C de CR. Effects of simple hysterectomy on bone loss. Sao Paulo Med J [Internet]. 1995 Nov. 11 [cited 2025 Oct. 16];113(6):1012-6. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/1746

Issue

Section

Original Article