Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus

Authors

  • Sérgio Mancini Nicolau Escola Paulista de Medicina
  • Nelson Valente Martins Escola Paulista de Medicina
  • Paulo Eduardo Ferraz Escola Paulista de Medicina
  • João Norberto Stávale Escola Paulista de Medicina
  • Wagner José Gonçalves Escola Paulista de Medicina
  • Edmund Chada Baracat Escola Paulista de Medicina
  • Geraldo Rodrigues de Lima Escola Paulista de Medicina

Keywords:

Peniscopy, papillomavirus, HPV, colposcopy

Abstract

INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.

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Author Biographies

Sérgio Mancini Nicolau, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Nelson Valente Martins, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Paulo Eduardo Ferraz, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

João Norberto Stávale, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Wagner José Gonçalves, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Edmund Chada Baracat, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Geraldo Rodrigues de Lima, Escola Paulista de Medicina

Universidade Federal de São Paulo, Department of Pathological Anatomy, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Department of Obstetrics and Gynecology, São Paulo, Brazil.

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Published

1997-01-01

How to Cite

1.
Nicolau SM, Martins NV, Ferraz PE, Stávale JN, Gonçalves WJ, Baracat EC, Lima GR de. Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus. Sao Paulo Med J [Internet]. 1997 Jan. 1 [cited 2025 Mar. 9];115(1):1330-5. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2076

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