Inhaled nitric oxide and high concentrations of oxygen in pediatrics patients with congenital cardiopathy and pulmonary hypertension

report of five cases

Authors

  • Werther Brunow de Carvalho Universidade Federal de São Paulo
  • Antonio Carlos Camargo Carvalho Universidade Federal de São Paulo
  • Gisele Limongeli Gurgueira Universidade Federal de São Paulo
  • Angela Mityo Ikeda Universidade Federal de São Paulo
  • June Ho Lee Universidade Federal de São Paulo
  • Dirceu Rodrigues Almeida Universidade Federal de São Paulo

Keywords:

Nitric Oxide, Pulmonary Hypertension, Congenital Cardiopathy

Abstract

Five patients with ages ranging from 6 months to 3 years were analyzed. All received inhaled nitric oxide (NO - 20 parts per million (ppm) ) and oxygen (0(2) - at a concentration of 90-95%) by means of an oxygen hood. Mean Pulmonary Artery Pressure (MPAP), Mean Aortic Pressure (MAoP), Pulmonary Vascular Resistance (PVR) and Systemic Vascular Resistance (SVR) were measured and the calculation of their relationship to pulmonary/systemic flow (Qp/Qs) was performed by the catheterization' of the femoral artery vein. Three patients presented reduction in PVR and increase in Qp/Qs. There were no systemic alterations or any side effect from using NO.

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Author Biographies

Werther Brunow de Carvalho, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departments of Pediatrics and Cardiology, São Paulo, São Paulo, Brazi.

Antonio Carlos Camargo Carvalho, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departments of Pediatrics and Cardiology, São Paulo, São Paulo, Brazil.

Gisele Limongeli Gurgueira, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departments of Pediatrics and Cardiology, São Paulo, São Paulo, Brazil.

Angela Mityo Ikeda, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departments of Pediatrics and Cardiology, São Paulo, São Paulo, Brazil.

June Ho Lee, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departments of Pediatrics and Cardiology, São Paulo, São Paulo, Brazil.

Dirceu Rodrigues Almeida, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departments of Pediatrics and Cardiology, São Paulo, São Paulo, Brazil.

References

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Published

1998-01-01

How to Cite

1.
Carvalho WB de, Carvalho ACC, Gurgueira GL, Ikeda AM, Lee JH, Almeida DR. Inhaled nitric oxide and high concentrations of oxygen in pediatrics patients with congenital cardiopathy and pulmonary hypertension: report of five cases. Sao Paulo Med J [Internet]. 1998 Jan. 1 [cited 2026 Sep. 19];116(1):1602-5. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2248

Issue

Vol. 116 No. 1 (1998)

Section

Original Article

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