Obstructive jaundice secondary to bile duct involvement with Hodgkin’s disease

a case report

Authors

  • Veruska Di Sena Universidade Federal de São Paulo — Escola Paulista de Medicina
  • Fernanda Prata Borges Martins Thuler Universidade Federal de São Paulo — Escola Paulista de Medicina
  • Erika Pereira Macedo Universidade Federal de São Paulo — Escola Paulista de Medicina
  • Gustavo Andrade de Paulo Universidade Federal de São Paulo — Escola Paulista de Medicina
  • Ermelindo Della Libera Universidade Federal de São Paulo — Escola Paulista de Medicina
  • Angelo Paulo Ferrari Universidade Federal de São Paulo — Escola Paulista de Medicina

Keywords:

Jaundice, Endoscopic retrograde cholangiopancreatography, Hodgkin’s disease, Lymphoma, Cholestasis

Abstract

CONTEXT: Obstructive jaundice due to lymphoma is very rare. It may be difficult to distinguish between this condition and a large number of causes of extrahepatic bile duct obstruction, even by endoscopic retrograde cholangiography. Its prognosis is poor. Combined chemotherapy and/or radiotherapy with bile duct drainage is a therapeutic option. CASE REPORT: We describe a case of obstructive jaundice as the initial presentation of Hodgkin’s disease. After chemotherapy and endoscopic bile duct stenting, it was noted that the enlarged lymph nodes, jaundice and bile duct dilation disappeared.

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Author Biographies

Veruska Di Sena, Universidade Federal de São Paulo — Escola Paulista de Medicina

MD. Research fellow in Gastroenterology, Universidade Federal de São Paulo — Escola Paulista de Medicina, São Paulo, Brazil.

Fernanda Prata Borges Martins Thuler, Universidade Federal de São Paulo — Escola Paulista de Medicina

MD. Research fellow in Gastroenterology, Universidade Federal de São Paulo — Escola Paulista de Medicina, São Paulo, Brazil.

Erika Pereira Macedo, Universidade Federal de São Paulo — Escola Paulista de Medicina

MD. Research fellow in Gastroenterology, Universidade Federal de São Paulo — Escola Paulista de Medicina, São Paulo, Brazil.

Gustavo Andrade de Paulo, Universidade Federal de São Paulo — Escola Paulista de Medicina

MD. Research fellow in Gastroenterology, Universidade Federal de São Paulo — Escola Paulista de Medicina, São Paulo, Brazil.

Ermelindo Della Libera, Universidade Federal de São Paulo — Escola Paulista de Medicina

MD. Attending physician, Endoscopy Unit, Universidade Federal de São Paulo — Escola Paulista de Medicina, São Paulo, Brazil.

Angelo Paulo Ferrari, Universidade Federal de São Paulo — Escola Paulista de Medicina

MD, PhD. Director of Endoscopy Unit, Universidade Federal de São Paulo — Escola Paulista de Medicina, São Paulo, Brazil.

References

Boddie AW, Eisenberg BL, Mullins JD, Schlichtemeier AL. The diagnosis and treatment of obstructive jaundice secondary to malignant lymphoma: a problem in multidisciplinary manage- ment. J Surg Oncol. 1980;14(2):111-23.

Yalçin S, Kars A, Sökmensüer C, Atahan L. Extrahepatic Hodgkin’s disease with intrahepatic cholestasis: report of two cases. Oncology. 1999;57(1):83-5.

Feller E, Schiffman FJ. Extrahepatic biliary obstruction by lymphoma. Arch Surg. 1990;125(11):1507-9.

Friedman CJ, Lambert MJ. Obstructive jaundice as initial presentation of non-Hodgkin’s lymphoma; value of internal percutaneous transhepatic biliary drainage. South Med J. 1981;74(8):1005-7.

Chu KM, Lai EC, Fan ST. Primary lymphoma presenting as intra-abdominal mass and obstructive jaundice. Am J Gastro- enterol. 1995;90(3):482-4.

Kerl K, Girardet C, Borisch B. A common B-cell precursor in composite lymphomas. N Engl J Med 1999;341(10):764-5.

Fend F, Quintanilla-Martínez L, Raffeld M. Composite lym- phoma. Hum Pathol. 2000;31(5):626-7.

Greiner TC, Gascoyne RD, Anderson ME, et al. Nodular lymphocyte-predominant Hodgkin’s disease associated with large-cell lymphoma: analysis of Ig gene rearrangements by V-J polymerase chain reaction. Blood. 1996;88(2):657-66.

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Published

2005-01-01

How to Cite

1.
Sena VD, Thuler FPBM, Macedo EP, Paulo GA de, Libera ED, Ferrari AP. Obstructive jaundice secondary to bile duct involvement with Hodgkin’s disease: a case report. Sao Paulo Med J [Internet]. 2005 Jan. 1 [cited 2025 May 11];123(1):30-2. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2301

Issue

Vol. 123 No. 1 (2005)

Section

Case Report

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