Hypomagnesemia in short bowel syndrome patients
Keywords:
Hypomagnesemia, Small gut syndrome, Intestine, HipomagnesemiaAbstract
CONTEXT: Magnesium support to small bowel resection patients. OBJECTIVE: Incidence and treatment of hypomagnesemia in patients with extensive small bowel resection. DESIGN: Retrospective study. SETTING: Metabolic Unit of the University Hospital Medical School of Ribeirão Preto, University of São Paulo, Brazil. PATIENTS: Fifteen patients with extensive small bowel resection who developed short bowel syndrome. MAIN MEASUREMENTS: Serum magnesium control of patients with bowel resection. Replacement of magnesium when low values were found. RESULTS: Initial serum magnesium values were obtained 21 to 180 days after surgery. Hypomagnesemia [serum magnesium below 1.5 mEq/l (SD 0.43)] was detected in 40% of the patients [1,19 mEq/l (SD 0.22)]. During the follow-up period, 66% of the patients presented at least two values below reference (1.50 mEq/l). 40% increased their serum values after magnesium therapy. CONCLUSION: Metabolic control of serum magnesium should be followed up after extensive small bowel resection. Hypomagnesemia may be found and should be controlled.
Downloads
References
Dutra-de-Oliveira JE, Marchini JS. Cięncias Nutricionais. Săo Paulo: Sarvier; 1998.
Shils ME, Olson JA, Shike M. Modern Nutrition in: Health and Disease, 8th ed. Philadelphia: USA; 1994.
Britton J, Pavord I, Richards K, et al. Dietary magnesium, lung function, wheezing, and hyper-reactivity in a random adult population sample. Lancet 1994;344:357-62.
National Research Council. Food and Nutrition Board. Recommended Dietary Allowances: 10th revised Edition. Washington, DC: National Academy of Sciences; 1989.
Mahan LK, Arlin MT. Krause Alimentos, Nutriçăo e Dietoterapia, 8th ed. Săo Paulo: Roca; 1995.
McLean RM. Magnesium and its therapeutic uses: a review. Am J Med 1994;96:63-76.
Woods KL, Fletcher S. Long-term outcome after intravenous magnesium sulfate in suspected acute myocardial-infarction - The Second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet 1994;343:816-9.
Eisenberg MJ. Magnesium deficiency and sudden death (editorial). Am Heart J 1992;124:544-9.
Lasserre B, Spoerri M, Moullet V, Theubet MP. Should magnesium therapy be considered for the treatment of coronary heart disease? II. Epidemiological evidence in outpatients with and without coronary heart disease. Magnes Res 1994;7:145-53.
Bernardi D, Dini FL, Azzarelli A, Giaconi A, Volterrani C, Lunardi M. Sudden cardiac death rate in an area characterized by high incidence of coronary artery disease and low hardness of drinking water. Angiology 1995;46:145-9.
Gartside PS, Glueck CJ. The important role of modifiable dietary and behavioral characteristics in the causation and prevention of coronary heart disease hospitalization and mortality: the prospective NHANES I follow-up study. J Am Coll Nutr 1995;14:71-9.
Altura BM, Zhang A, Altura BT. Magnesium, hypertensive vascular diseases, atherogenesis, subcellular compartmentation of Ca2+ and Mg2+ and vascular contractility. Miner Electrolyte Metab 1993;19:323-36.