Bronchial oncocytoma
Keywords:
Oncocytoma, Bronchial, PulmonaryAbstract
CONTEXT: Oncocytomas are generally small and present slow growth. Finding of the tumor usually occurs incidentally. Their incidence is higher among male patients. Oncocytomas in mucous bronchial glands are extremely rare. CASE REPORT: A 35-year-old male who presented bronchial oncocytoma. The tumor was found after bronchoscopy that investigated an atelectasis of the upper left lobe. Histological examination with optical microscopy revealed a mature neoplasm formed by ovoid cells with thin, granular, eosinophilic cytoplasm and small nuclei similar to oncocytes. Electron microscopy showed mitochondrial hyperplasia. A three-year follow-up after thoracotomy followed by lobectomy and removal of the bronchial tumor was uneventful.
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References
Hamperl H. Benign and malignant oncocytoma. Cancer 1962;15:1019-27.
Cwierzyk TA, Glasberg SS, Virshup MA, et al. Pulmonary oncocytoma: report of a case with cytologic, histologic and electron microscopic study. Acta Cytol 1985;29:620-3.
Fine G, Chang CH. Adenoma of type 2 pneumocytes with oncocytic features. Arch Pathol Lab Med 1991;115:797-801.
Morra MN, Das S. Renal oncocytoma: a review of histogenesis, histopathology, diagnosis and treatment. J Urol 1993;150:295-302.
Tashiro Y, Iwata Y, Nabae T, Manabe H. Pulmonary oncocytoma: report of a case in conjunction with an immunohistochemical and ultrastructural study. Pathol Int 1995;45(6):448-51.
Fechner RE, Bentinck BR. Ultrastructure of bronchial oncocytoma. Cancer 1973;1:1451-7.
Nielsen AL. Malignant bronchial oncocytoma: case report and review of the literature. Hum Pathol 1985;16(8):852-4.
Kumar PV, Monabati A. Bronchial oncocytoma diagnosed by brushing cytology [Letter]. Acta Cytol 1998;42(4):1056-7.