Darier's disease
a new paradigm for genetic studies in psychiatric disorders
Keywords:
Darier's disease, Depression, Psychiatry, GeneticsAbstract
CONTEXT: One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes. CASE REPORT: A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be located on chromosome 12.
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References
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