Effects of bariatric surgery on renal function: a retrospective cohort study comparing one-year outcomes between one-anastomosis gastric bypass and Roux-en-Y gastric bypass

Victor Kenzo Ivano; Marcelo Hatto; Fernanda Teramoto; Paolla Ravida Alves de Macedo; Martinho Antonio Gestic; Murillo Pimentel Utrini; Felipe David Mendonça Chaim; Almino Cardoso Ramos; Francisco Callejas Neto; Elinton Adami Chaim; Everton Cazzo

Authors

Victor Kenzo Ivano Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0003-0160-2372
Marcelo Hatto Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0009-0002-2592-9839
Fernanda Teramoto Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0009-0007-3035-3076
Paolla Ravida Alves de Macedo Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0009-0007-3414-3236
Martinho Antonio Gestic Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0002-4527-676X
Murillo Pimentel Utrini Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0002-6597-4258
Felipe David Mendonça Chaim Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0002-4195-6143
Almino Cardoso Ramos Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0001-6805-1750
Francisco Callejas Neto Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0001-6023-187X
Elinton Adami Chaim Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0003-4627-0631
Everton Cazzo Universidade Estadual de Campinas, Campinas, São Paulo, Brazil https://orcid.org/0000-0002-5804-1580

Keywords:

Gastric bypass, Bariatric surgery, Glomerular filtration rate, Kidney diseases, Obesity, One-anastomosis gastric bypass, Roux-en-Y gastric bypass, Renal function

Abstract

BACKGROUND: Evidence on the effect of one-anastomosis gastric bypass (OAGB) on renal function is limited. OBJECTIVE: To compare the evolution of estimated renal function observed 1 year after OAGB and Rouxen-Y gastric bypass (RYGB) in individuals with obesity. DESIGN AND SETTING: Observational, analytical, and retrospective cohort study. Tertiary-level university hospital. METHODS: This study used a prospectively collected database of individuals who consecutively underwent bariatric surgery. Renal function was assessed by calculating the estimated glomerular filtration rate (eGFR), according to the Chronic Kidney Disease Epidemiology Collaboration. The one-year variation in the eGFR was compared between the procedures. RESULTS: No significant differences in age, sex, obesity-associated conditions, or body mass index were observed among individuals who underwent either OAGB or RYGB. OAGB led to a significantly higher percentage of total (P = 0.007) and excess weight loss (P = 0.026). Both OAGB and RYGB led to significantly higher values of eGFR (103.9 ± 22 versus 116.1 ± 13.3; P = 0.007, and 102.4 ± 19 versus 113.2 ± 13.3;P < 0.001, respectively). The one-year variation in eGFR was 11 ± 16.2% after OAGB and 16.7 ± 26.3% after RYGB (P = 0.3). Younger age and lower baseline eGFR were independently associated with greater postoperative improvement in renal function (P < 0.001).CONCLUSION: Compared with RYGB, OAGB led to an equivalent improvement in renal function 1 year after the procedure, along with greater weight loss.

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Author Biographies

Victor Kenzo Ivano, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD. Postgraduate Student, Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Marcelo Hatto, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD. Postgraduate Student, Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Fernanda Teramoto, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD. Medical Resident, Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Paolla Ravida Alves de Macedo, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD. Medical Resident, Department of Surgery School of Medical Sciences, Universidade Estadual de Campinas
(UNICAMP), Campinas (SP), Brazil.

Martinho Antonio Gestic, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD, MSc. Assistant lecturer, Department of Surgery, School of Medical Sciences, Universidade State University of Campinas (UNICAMP), Campinas (SP), Brazil.

Murillo Pimentel Utrini, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD. Assistant Lecturer, Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Felipe David Mendonça Chaim, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD, PhD. Assistant Lecturer, Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Almino Cardoso Ramos, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD, PhD. Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Francisco Callejas Neto, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD, MSc. Assistant Professor, Department of Surgery, School of Medical Sciences, Universidade Estadual de
Campinas (UNICAMP), Campinas (SP), Brazil.

Elinton Adami Chaim, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD, PhD. Full Professor, Department of Surgery, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil.

Everton Cazzo, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

MD, PhD. Associate Professor, Department of Surgery, School of Medical Sciences, Universidade Estadual de
Campinas (UNICAMP), Campinas (SP), Brazil.

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Effects of bariatric surgery on renal function: a retrospective cohort study comparing one-year outcomes between one-anastomosis gastric bypass and Roux-en-Y gastric bypass

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Author Biographies

Victor Kenzo Ivano, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Marcelo Hatto, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Fernanda Teramoto, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Paolla Ravida Alves de Macedo, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Martinho Antonio Gestic, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Murillo Pimentel Utrini, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Felipe David Mendonça Chaim, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Almino Cardoso Ramos, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Francisco Callejas Neto, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Elinton Adami Chaim, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

Everton Cazzo, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

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