Non-surgical facial harmonization for gender affirmation and psychosocial well-being in transmasculine persons: an exploratory mixed-methods study

Authors

Keywords:

Transmasculine persons, Gender-affirming care, Facial recognition, Hyaluronic acid, Health promotion, Facial masculinization, Gender congruence, Non-surgical gender affirmation, Transgender health, Body image satisfaction, Psychosocial outcomes

Abstract

BACKGROUND: Facial appearance plays a central role in gender recognition and identity congruence, particularly among transmasculine individuals. Although the demand for gender-affirming care has increased, evidence regarding the psychosocial implications of nonsurgical facial masculinization using hyaluronic acid remains limited, especially within public health systems.

OBJECTIVES: To describe the subjective and psychosocial experiences related to nonsurgical facial harmonization with hyaluronic acid among transmasculine individuals receiving care in public health settings.

DESIGN AND SETTING: A mixed-methods exploratory study with a qualitative core component was conducted in a public, gender-affirming outpatient clinic in Salvador.

METHODS: Six transmasculine patients participated in semi-structured interviews. The FACE-Q Satisfaction with Facial Appearance Overall Scale (SFAOS) and Beck Anxiety Inventory (BAI) were administered before and 30 days after the procedure as complementary quantitative measures. Qualitative data were analyzed using thematic content analysis based on Bardin’s framework, with sampling guided by theoretical saturation.

RESULTS: Participants reported perceived reductions in facial dysphoria, improvements in self-perception, and greater social confidence after the procedure. Complementary quantitative measures indicated consistent short-term increases in facial satisfaction scores and a trend toward reduced anxiety.

CONCLUSIONS: In this exploratory study, nonsurgical facial harmonization with hyaluronic acid was associated with short-term improvements in self-perceived facial satisfaction and psychosocial comfort among transmasculine participants. Given the small sample size and short follow-up period, these findings should be interpreted as preliminary. Larger studies with longer follow-up periods and comparative designs are warranted to evaluate the durability and generalizability of our findings.

Downloads

Download data is not yet available.

Author Biographies

Liliane Lins-Kusterer, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

PhD, Human Pathology. Maxillofacial Surgeon, Departamento de Medicina Preventiva e Social (DMPS), Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil.

Victor Augusto Bastos e Silva, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

Undergraduate student. Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil.

João Gabriel Macedo Briglia, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

Undergraduate student. Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil.

José Valber Lima Meneses, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

PhD, Surgery. Departamento de Cirurgia, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil.

Larissa do Nascimento Sampaio Celestino, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

DDS. Hospital Dentistry Resident, Hospital Universitário Professor Edgard Santos (HUPES), Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil.

Iza Maura Alves Travenzoli, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

DDS. Hospital Dentistry Resident, Hospital Universitário Professor Edgard Santos (HUPES), Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil.

Rodrigo Fernandes Weyll Pimentel, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

MPH. Departamento de Saúde da Família, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (FMB-UFBA), Salvador (BA), Brazil

References

Dhingra N, Bonati LM, Wang EB, Chou M, Jagdeo J. Medical and aesthetic procedural dermatology recommendations for transgender patients undergoing transition. J Am Acad Dermatol. 2019 Jun;80(6):1712–1. PMID: 30678999; https://doi.org/10.1016/j.jaad.2018.05.1259.

De Boulle K, Furuyama N, Heydenrych I, et al. Considerations for the use of minimally invasive aesthetic procedures for facial remodeling in transgender individuals. Clin Cosmet Investig Dermatol. 2021 May 13;14:513–25. PMID: 34012284; https://doi.org/10.2147/CCID.S304032.

Cronin BJ, Fadich S, Lee JC. Assessing preferences of facial appearance in transgender and gender nonbinary patients. Aesthetic Plast Surg. 2024 Feb;48(4):621–32. PMID: 37935961; https://doi.org/10.1007/s00266-023-03715-2.

Lins-Kusterer L, Azevedo JF, Carvalho FM. Non-surgical procedures for facial gender reassignment: integrative review. Braz J Hea Rev. 2025 Feb 27;8(1):e77989. https://doi.org/10.34119/bjhrv8n1-505.

Ascha M, Swanson MA, Massie JP, et al. Nonsurgical management of facial masculinization and feminization. Aesthet Surg J. 2019 Apr 8;39(5):NP123–NP137. PMID: 30383180; https://doi.org/10.1093/asj/sjy253.

Wu GT, Wong A, Bloom JD. Injectable treatments and nonsurgical aspects of gender affirmation. Facial Plast Surg Clin North Am. 2023 Aug;31(3):399–406. PMID: 37348983; https://doi.org/10.1016/j.fsc.2023.04.004.

Fagien S, Bertucci V, von Grote E, Mashburn JH. Rheologic and physicochemical properties used to differentiate injectable hyaluronic acid filler products. Plast Reconstr Surg. 2019 Apr;143(4):707e–720e. PMID: 30921116; https://doi.org/10.1097/PRS.0000000000005429.

Vaismoradi M, Turunen H, Bondas T. Content analysis and thematic analysis: implications for conducting a qualitative descriptive study. Nurs Health Sci. 2013 Sep;15(3):398–405. PMID: 23480423; https://doi.org/10.1111/nhs.12048.

Klassen AF, Cano SJ, Schwitzer JA, Scott AM, Pusic AL. FACE-Q scales for health-related quality of life, early life impact, satisfaction with outcomes, and decision to have treatment: development and validation. Plast Reconstr Surg. 2015 Feb;135(2):375–86. PMID: 25626785; https://doi.org/10.1097/PRS.0000000000000895.

Kabacoff RI, Segal DL, Hersen M, Van Hasselt VB. Psychometric properties and diagnostic utility of the Beck Anxiety Inventory and the State-Trait Anxiety Inventory with older adult psychiatric outpatients. J Anxiety Disord. 1997 Jan-Feb;11(1):33–47. PMID: 9131880; https://doi.org/10.1016/s0887-6185(96)00033-3.

Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. 2007 Dec;19(6):349–57. PMID: 17872937; https://doi.org/10.1093/intqhc/mzm042.

Downloads

Published

2026-05-14

How to Cite

1.
Lins-Kusterer L, Silva VAB e, Briglia JGM, Meneses JVL, Celestino L do NS, Travenzoli IMA, Pimentel RFW. Non-surgical facial harmonization for gender affirmation and psychosocial well-being in transmasculine persons: an exploratory mixed-methods study. Sao Paulo Med J [Internet]. 2026 May 14 [cited 2026 Jun. 10];144(2):1-8. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/3274

Issue

Section

Original Article