Christiaan Neethling Barnard — A controversial figure: Courage, innovation, and the global impact of the world’s first human heart transplant

Authors

Keywords:

Christiaan Neethling Barnard, Heart transplant

Abstract

In the early hours of May 26, 1968, Professor Euryclides de Jesus Zerbini and his associates performed the first human heart transplantation in Brazil. Years prior, the possibility of such operation had been proposed to him twice; however, he had considered it premature.
In December 3, 1967, Dr. Christiaan Neethling Barnard performed the first human-to-human heart transplantation worldwide. The following day, Dr. Zerbini began a series of meetings to prepare his team. As in several centers worldwide, the Brazilian team decided to pursue transplantation inspired by Barnard’s achievement.

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Author Biography

Noedir Antônio Groppo Stolf, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, São Paulo, Brazil

Senior Professor of Cardiovascular Surgery, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo (SP), Brazil.

References

Stolf NAG. History of Heart Transplantation: a Hard and Glorious Journey. Braz J Cardiovasc Surg. 2017;32(5):423-7. PMID: 29211224; https://doi. org/10.21470/1678-9741-2017-0508.

Barnard CN. The operation. A human cardiac transplant: an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town. S Afr Med J. 1967;41(48):1271-4. PMID: 4170370.

Hardy JD, Kurrus FD, Chaves CM, et al. Heart transplantation in man: developmental studies and report of a case. JAMA. 1964;188(13):1132-40. PMID: 14163110; https://doi.org/10.1001/jama.1964.03060390034008.

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Published

2026-05-14

How to Cite

1.
Stolf NAG. Christiaan Neethling Barnard — A controversial figure: Courage, innovation, and the global impact of the world’s first human heart transplant. Sao Paulo Med J [Internet]. 2026 May 14 [cited 2026 Jun. 10];144(2):1-2. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/3619

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Section

Letter to the Editor