What are the perspectives for blood donations and blood component transfusion worldwide? A systematic review of time series studies
Keywords:
Blood transfusion, Aging, Blood supply [subheading]Abstract
BACKGROUND: Analysis of the literature suggests that changes relating to blood donations and blood component transfusion are occurring due to the aging of the population. OBJECTIVE: To gain better understanding of the demand and supply of these inputs over time, and to identify the main associated demographic characteristics. DESIGN AND SETTING: Systematic review conducted on time series relating to blood donations and blood component transfusions worldwide. METHODS: A systematic review of the literature was conducted based on articles that presented time series relating to blood donation or blood component transfusion. RESULTS: We found 1,814 articles. After the deletion process, only thirteen were read. Overall, these suggested that there is increasing demand for blood components and decreasing donation. The existence of seasonality regarding blood donation was pointed out. Men usually donated more blood and demanded more blood components than women. Approximately 50% of blood transfusions were performed in people aged ≥ 60 years. CONCLUSIONS: This analysis on articles that presented time series relating to blood donations and blood component transfusion showed that aging of the population was the main factor associated with the increasing demand for blood and the decreasing supply of blood. SYSTEMATIC REVIEW REGISTRATION: CRD42019118995.
Downloads
References
Reis CS, Noronha KVMS, Wajnman S, Ajnman S. Envelhecimento populacional e gastos com internação do SUS: uma análise realizada para o Brasil entre 2000 e 2010. Revista Brasileira de Estudos de População. 2016;33(3):591-612. doi: 10.20947/S0102-30982016c0007.
Azevedo EMM, Shander A. Porque e como racionalizar o uso de sangue alogênico em cirurgia. Semina: Ciências Biológicas e da Saúde. 2002;23(1):87-92. doi: 10.5433/1679-0367.2002v23n1p87.
Novaretti MCZ. Importância dos carregadores de oxigênio livre de células [Oxygen carriers free of cells in transfusion medicine]. Revista Brasileira de Hematologia e Hemoterapia. 2007;29(4):394-405. doi: 10.1590/S1516-84842007000400014.
Souza HJB, Moitinho RF. Estratégias para redução do uso de hemoderivados em cirurgia cardiovascular [Strategies to reduce the use of blood components in cardiovascular surgery]. Revista Brasileira de Cirurgia Cardiovascular. 2008;23(1):53-9. doi: 10.1590/S0102-76382008000100010.
Brum DEL. Racionalizar a transfusão de hemocomponentes: benefícios a pacientes, instituições e operadoras de planos de saúde [Rationalization of blood transfusion benefits to patients, hospitals and health care providers]. Revista da AMRIGS.2011;55(1):76-82. Available from: Available from: https://docplayer.com.br/10110621-Racionalizar-a-transfusao-de-hemocomponentes-beneficios-a-pacientes-instituicoes-e-operadoras-de-planos-de-saude.html Accessed in 2019 (Oct 1).
Sweeney JD, Rizk Y. Manual Prático de Hemoterapia. Rio de Janeiro: Editora Revinter; 2005. p. 4-8. ISBN: 8573098376.
Santos AA, Silva JP, Silva LF, et al. Therapeutic options to minimize allogeneic blood transfusions and their adverse effects in cardiac surgery: A systematic review. Rev Bras Cir Cardiovasc. 2014;29(4):606-21. PMID: 25714216; doi: 10.5935/1678-9741.20140114.
Ali A, Auvinen MK, Rautonen J. The aging population poses a global challenge for blood services. Transfusion. 2010;50(3):584-8. PMID: 19912582; doi: 10.1111/j.1537-2995.2009.02490.x.
Borkent-Raven BA, Janssen MP, van der Poel CL, et al. The PROTON study: profiles of blood product transfusion recipients in the Netherlands. Vox Sang. 2010;99(1):54-64. PMID: 20202179; doi: 10.1111/j.1423-0410.2010.01312.x.
Borkent-Raven BA, Janssen MP, Van Der Poel CL. Demographic changes and predicting blood supply and demand in the Netherlands. Transfusion. 2010;50(11):2455-60. PMID: 20529000; doi: 10.1111/j.1537-2995.2010.02716.x.
Carneiro-Proietti AB, Sabino EC, Sampaio D, et al. Demographic profile of blood donors at three major Brazilian blood centers: results from the International REDS-II study, 2007 to 2008. Transfusion. 2010;50(4):918-25. PMID: 20003051; doi: 10.1111/j.1537-2995.2009.02529.x.
Crawford SO, Reich NG, An MW, et al. Regional and temporal variation in American Red Cross blood donations, 1995 to 2005. Transfusion. 2008;48(8):1576-83. PMID: 18503618; doi: 10.1111/j.1537-2995.2008.01755.x.
Currie CJ, Patel TC, McEwan P, Dixon S. Evaluation of the future supply and demand for blood products in the United Kingdom National Health Service. Transfus Med. 2004;14(1):19-24. PMID: 15043589; doi: 10.1111/j.0958-7578.2004.00475.x.
Drackley A, Newbold BK, Paez A, Heddle N. Forecasting Ontario’s blood supply and demand. Transfusion. 2012;52(2):366-74. PMID: 21810099; doi: 10.1111/j.1537-2995.2011.03280.x.
Greinacher A, Fendrich K, Alpen U, Hoffmann W. Impact of demographic changes on the blood supply: Mecklenburg-West Pomerania as a model region for Europe. Transfusion. 2007;47(3):395-401. PMID: 17319818; doi: 10.1111/j.1537-2995.2007.01129.x.
Greinacher A, Fendrich K, Hoffmann W. Demographic Changes: The Impact for Safe Blood Supply. Transfus Med Hemother. 2010;37(3):141-8. PMID: 20737017; doi: 10.1159/000313949.
Greinacher A, Fendrich K, Brzenska R, Kiefel V, Hoffmann W. Implications of demographics on future blood supply: a population-based cross-sectional study. Transfusion. 2011;51(4):702-9. PMID: 20849411; doi: 10.1111/j.1537-2995.2010.02882.x.
Oliveira CDL, Almeida-Neto C, Liu EJ, et al. Temporal distribution of blood donations in three Brazilian blood centers and its repercussion on the blood supply. Revista Brasileira de Hematologia e Hemoterapia. 2013;35(4):246-51. doi: 10.5581/1516-8484.20130071.
Pfuntner A, Wier LM, Stocks C. Most Frequent Procedures Performed in US Hospitals, 2011: Statistical Brief #165. Healthcare Cost and Utilization Project (HCUP) Statistical Briefs [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013. PMID: 24354027.
Volken T, Buser A, Castelli D, et al. Red blood cell use in Switzerland: trends and demographic challenges. Blood Transfus. 2018;16(1):73-82. PMID: 27723455; doi: 10.2450/2016.0079-16.
Rodrigues RSM, Reibnitz KS. Estratégias de captação de doadores de sangue: uma revisão integrativa da literatura [Strategies for attracting blood donors: an integrative literature review]. Texto & Contexto Enfermagem. 2011;20(2). doi: 10.1590/S0104-07072011000200022.
Pereira JR, Veloso e Sousa C, Matos EB, et al. Doar ou não doar, eis a questão: uma análise dos fatores críticos da doação de sangue [To donate or not donate, that is the question: an analysis of the critical factors of blood donation]. Ciência & Saúde Coletiva. 2016;21(8):2475-84. doi: 10.1590/1413-81232015218.24062015.
Carlesso L, Guimarães RFS, Silva SL, et al. Estratégias implementadas em hemocentros para aumento da doação de sangue [Strategies implemented in hemotherapy services to increase blood donation]. Revista Brasileira de Promoção da Saúde. 2017;30(2):213-20. doi: 10.5020/18061230.2017.p213.
Shander A. Optimizing transfusion in vascular surgery: is bloodless surgery an option? Vascular. 2008;16 Suppl 1:S37-47. PMID: 18544304.
Kassakian SZ, Yackel TR, Deloughery T, Dorr DA. Clinical Decision Support Reduces Overuse of Red Blood Cell Transfusions: Interrupted Time Series Analysis. Am J Med. 2016; 129(6):636.e13-20. PMID: 26873112; doi: 10.1016/j.amjed.2016.01.024.
Thomson A, Farmer S, Hofmann A, Isbister J, Shander A. Patient blood management - a new paradigm for transfusion medicine? International Society of Blood Transfusion. 2009;4(2):423-35. doi: 10.1111/j.1751-2824.2009.01251.x.