Quality of life and psychometric evaluation of patients diagnosed with irritable bowel syndrome

an observational cohort study

Autores

Palavras-chave:

Anxiety, Depression, Quality of life, Irritable bowel syndrome

Resumo

BACKGROUND: Very few data are available for evaluating health-related quality of life among people with irritable bowel syndrome (IBS) and even fewer data are available in relation to anxiety and depression status among these patients. OBJECTIVES: To evaluate the quality of life, anxiety and depression status of patients with IBS. DESIGN AND SETTING: Observational cohort study conducted in a tertiary-care university hospital.METHODS: Patients who had recently been diagnosed with IBS and who had been followed up for IBS-specific treatment for at least three months were included. A quality of life (QoL) survey, the Beck Anxiety Index (BAI) and the Hamilton Depression Index (HAM-D) were applied to the patients. RESULTS: In total, 274 patients with IBS were included in the study cohort. These patients presented very high baseline scores for anxiety and depression, and very poor QoL results. CONCLUSION: Our study showed that IBS had a very high impact on these patients, regarding their anxiety and depression levels, alongside very poor results relating to quality of life.

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Biografia do Autor

Alp Yildiz, Yenimahalle Training and Research Hospital, Yildirim Beyazit University

MD. General Surgeon, Department of General Surgery, Yenimahalle Training and Research Hospital, Yildirim Beyazıt University, Ankara, Turkey.

Aybala Yildiz, Yenimahalle Training and Research Hospital, Yildirim Beyazit University

MD. Psychiatrist, Private Emre Kizil Psychiatry Clinic, Cankaya, Ankara, Turkey.

Aybala Yildiz, Yenimahalle Training and Research Hospital, Yildirim Beyazit University

MD, PhD. Associate Professor, Department of General Surgery, Yenimahalle Training and Research Hospital, Yildirim Beyazıt University, Ankara, Turkey.

Referências

Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol. 2012;10(7):712-721.e4. PMID: 22426087; doi: 10.1016/j.cgh.2012.02.029.

Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology. 2002;122(5):1500-11. PMID: 11984534; doi: 10.1053/gast.2002.32978.

Yang TY, Chen CS, Lin CL, et al. Risk for Irritable Bowel Syndrome in Fibromyalgia Patients: A National Database Study. Medicine (Baltimore). 2017;96(14):e6657. PMID: 28383443; doi: 10.1097/MD.0000000000006657.

Sperber AD, Atzmon Y, Neumann L, et al. Fibromyalgia in the irritable bowel syndrome: studies of prevalence and clinical implications. Am J Gastroenterol. 1999;94(12):3541-6. PMID: 10606316; doi: 10.1111/j.1572-0241.1999.01643.x.

El-Serag HB, Olden K, Bjorkman D. Health-related quality of life among persons with irritable bowel syndrome: a systematic review. Aliment Pharmacol Ther. 2002;16(6):1171-85. PMID: 12030961; doi: 10.1046/j.1365-2036.2002.01290.x.

Fond G, Loundou A, Hamdani N, et al. Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis. Eur Arch Psychiatry Clin Neurosci. 2014;264(8):651-60. PMID: 24705634; doi: 10.1007/s00406-014-0502-z.

Veale D, Kavanagh G, Fielding JF, Fitzgerald O. Primary fibromyalgia and the irritable bowel syndrome: different expressions of a common pathogenetic process. Br J Rheumatol. 1991;30(3):220-2. PMID: 2049586; doi: 10.1093/rheumatology/30.3.220.

Lee S, Wu J, Ma YL, et al. Irritable bowel syndrome is strongly associated with generalized anxiety disorder: a community study. Aliment Pharmacol Ther. 2009;30(6):643-51. PMID: 19552631; doi: 10.1111/j.1365-2036.2009.04074.x.

Lee C, Doo E, Choi JM, et al. The Increased Level of Depression and Anxiety in Irritable Bowel Syndrome Patients Compared with Healthy Controls: Systematic Review and Meta-analysis. J Neurogastroenterol Motil. 2017;23(3):349-62. PMID: 28672433; doi: 10.5056/jnm16220.

Zamani M, Alizadeh‐Tabari S, Zamani V. Systematic review with meta‐analysis: the prevalence of anxiety and depression in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 2019;50(2):132-43. PMID: 31157418; doi: 10.1111/apt.15325.

Tollefson GD, Tollefson SL, Pederson M, Luxenberg M, Dunsmore G. Comorbid irritable bowel syndrome in patients with generalized anxiety disorder and major depression. Ann Clin Psychiatry. 1991;3(3):215-22. Available from: Available from: https://www.tandfonline.com/doi/abs/10.3109/10401239109147994 Accessed in 2020 (Apr 17).

Masand PS, Kaplan DS, Gupta S, et al. Major depression and irritable bowel syndrome: is there a relationship? J Clin Psychiatry. 1995;56(8):363-5. PMID: 7635853.

Mayer EA, Tillisch K, Bradesi S. Review article: modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease. Aliment Pharmacol Ther. 2006;24(6):919-33. PMID: 16948804; doi: 10.1111/j.1365-2036.2006.03078.x.

Eker MÇ, Eker ÖD. Depresyon ve İrritabl Barsak Sendromu Birlikteliğinin Nörobiyolojisi [Neurobiology of Depression and Irritable Bowel Syndrome Comorbidity]. Psikiyatride Güncel Yaklaşımlar. 2009;1:120-31. Available from: Available from: http://www.psikguncel.org/archives/vol1/no2/cap_1_10.pdf Accessed in 2020 (May 8).

Musial F, Hauser W, Langhorst J, Dobos G, Enck P. Psychophysiology of visceral pain in IBS and health. J Psychosom Res. 2008;64(6):589-97. PMID: 18501259; doi: 10.1016/j.jpsychores.2008.02.024.

O’Mahony SM, Clarke G, Dinan TG, Cryan JF. Irritable Bowel Syndrome and Stress-Related Psychiatric Co-morbidities: Focus on Early Life Stress. Handb Exp Pharmacol. 2017;239:219-46. PMID: 28233180; doi: 10.1007/164_2016_128.

Schwetz I, McRoberts JA, Coutinho SV, et al. Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats. Am J Physiol Gastrointest Liver Physiol. 2005;289(4):G704-12. PMID: 15994424; doi: 10.1152/ajpgi.00498.2004.

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Publicado

2020-08-06

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1.
Yildiz A, Yildiz A, Yildiz A. Quality of life and psychometric evaluation of patients diagnosed with irritable bowel syndrome: an observational cohort study. Sao Paulo Med J [Internet]. 6º de agosto de 2020 [citado 16º de outubro de 2025];138(4):282-6. Disponível em: https://periodicosapm.emnuvens.com.br/spmj/article/view/649

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