Inflammatory myofibroblastic tumor of the prostate after transurethral resection of the prostate with negative expression of anaplastic lymphoma kinase
a case report
Keywords:
Granuloma, plasma cell, Inflammation, ProstateAbstract
CONTEXT: Inflammatory myofibroblastic tumors are a rare type of soft-tissue tumor. Inflammatory myo- fibroblastic tumors are characterized by rearrangements involving the anaplastic lymphoma kinase gene locus on 2p23. CASE REPORT: We report the case of a 67-year-old Chinese male who presented with dysuria and fever. Magnetic resonance imaging showed an irregular prostatic mass with an isointense signal and obscure boundary. Histopathological evaluation showed that the mass consisted mainly of spindle-shaped cells. Immunohistochemical evaluation showed that the tumor cells were negative for anaplastic lymphoma kinase. CONCLUSIONS: Inflammatory myofibroblastic prostate tumors are rare lesions with unclear etiology. The pathological diagnosis is very important.
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References
Zhang HH, Qi F, Zu XB, et al. Recurrence of inflammatory myofibroblastic tumor in bladder secondary to prostate treated with laparoscopic radical cystectomy. Med Sci Monit. 2012;18(8):CS63-66. PMID: 22847204.
Liu C, Zhao X, Zhao Z, et al. Malignant inflammatory myofibroblastic tumor of the prostate. J Clin Oncol. 2013;31(10):e144-7. PMID: 23401456.
Zhao HD, Wu T, Wang JQ, et al. Primary inflammatory myofibroblastic tumor of the breast with rapid recurrence and metastasis: A case report. Oncol Lett. 2013;5(1):97-100. PMID: 23255901.
Surabhi VR, Chua S, Patel RP, et al. Inflammatory Myofibroblastic Tumors: Current Update. Radiol Clin North Am. 2016;54(3):553-63. PMID: 27153788.
González MG, Vela D, Álvarez M, Caramés J. Inflammatory myofibroblastic duodenal tumor: A rare cause of massive intestinal bleeding. Cancer Biomark. 2016;16(4):555-7. PMID: 27002758.
Lovly CM, Gupta A, Lipson D, et al. Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions. Cancer Discov. 2014;4(8):889-95. PMID: 24875859.
Zhou Y, Zhu J, Zhang Y, Jiang J, Jia M. An inflammatory myofibroblastic tumour of the breast with ALK overexpression. BMJ Case Rep. 2013. pii: bcr0720114474. PMID: 23386486.
Khanafshar E, Phillipson J, Schammel DP, et al. Inflammatory myofibroblastic tumor of the breast. Ann Diagn Pathol. 2005;9(3):123-9. PMID: 15944952.
Takayama Y, Yabuuchi H, Matsuo Y, et al. Computed tomographic and magnetic resonance features of inflammatory myofibroblastic tumor of the lung in children. Radiat Med. 2008;26(10):613-7. PMID: 19132493.
Gao F, Zhong R, Li GH, Zhang WD. Computed tomography and magnetic resonance imaging findings of inflammatory myofibroblastic tumors of the head and neck. Acta Radiol. 2014;55(4):434-40. PMID: 23966365.
Germanidis G, Xanthakis I, Tsitouridis I, et al. Regression of inflammatory myofibroblastic tumor of the gastrointestinal tract under infliximab treatment. Dig Dis Sci. 2005;5(2):262-5. PMID: 15745083.
Li HB, Xu YM, Yu JJ. Diagnostic puzzle of inflammatory pseudotumor of the urinary bladder: a case report with brief literature review. South Med J. 2010;103(6):563-6. PMID: 20710142.
Coffin CM, Hornick JL, Fletcher CD. Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases. Am J Surg Pathol. 2007;31(4):509-20. PMID: 17414097.
Teoh JY, Chan NH, Cheung HY, Hou SS, Ng CF. Inflammatory myofibroblastic tumors of the urinary bladder: a systematic review. Urology. 2014;84(3):503-8. PMID: 25168523.
Satomi T, Watanabe M, Matsubayashi J, Nagao T, Chiba H. A successfully treated inflammatory myofibroblastic tumor of the mandible with long-term follow-up and review of the literature. Med Mol Morphol. 2010;43(3):185-91. PMID: 20857269.