Diagnostic discrepancies between emergency department admissions and hospital discharges among older adults
secondary analysis on a population-based survey
Keywords:
Aged, Diagnosis, Emergency medicine, Hospital medicine, Diagnostic errors, Patient safetyAbstract
BACKGROUND: Older adults frequently experience nonspecific clinical features. However, there is limited evidence on how often admission diagnoses for hospitalized older patients are incorrect, potentially leading to treatment delays. OBJECTIVES: To determine the consistency between hospital admission and discharge diagnoses, and identify factors associated with diagnostic discrepancies in older adults. DESIGN AND SETTING: Population-based cohort study in the United States. We included adults aged ≥ 18 years who were admitted from emergency departments (EDs) to hospitals, identified using the 2005-2010 National Hospital Ambulatory Medical Survey, a nationally representative survey METHODS: Three admission diagnoses and the principal discharge diagnosis were captured and classified as discrepant if they involved considerably different conditions within the same organ system, or different organ systems altogether. RESULTS: Each year, 12 million adults were hospitalized following ED visits in the United States; 45% were aged ≥ 65 years. These patients’ mean age was 79 years and 58% were women. Diagnostic discrepancies between admission and discharge were more common among adults ≥ 65 years (12.5 versus 8.3%; P < 0.001). Certain admission diagnoses had particularly high rates of diagnostic discrepancies: 26-27% of patients presenting with mental disorders or with endocrine and metabolic diseases had substantial diagnostic discrepancies between admission and discharge. Substantial diagnostic discrepancy was independently associated with longer hospitalization and higher in-hospital mortality. CONCLUSION: One out of eight older adults hospitalized from EDs was discharged with a principal diagnosis differing considerably from the admission diagnosis. Given that missed or delayed diagnoses are a critical safety problem, clinicians should be vigilant and frequently cogitate alternative diagnostic possibilities.
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Pines JM, Mullins PM, Cooper JK, Feng LB, Roth KE. National trends in emergency department use, care patterns, and quality of care of older adults in the United States. J Am Geriatr Soc. 2013;61(1):12-7. PMID: 23311549; doi: 10.1111/jgs.12072.
Samaras N, Chevalley T, Samaras D, Gold G. Older patients in the emergency department: a review. Ann Emerg Med. 2010;56(3):261-9. PMID: 20619500; doi: 10.1016/j.annemergmed.2010.04.015.
Aminzadeh F, Dalziel WB. Older adults in the emergency department: a systematic review of patterns of use, adverse outcomes, and effectiveness of interventions. Ann Emerg Med. 2002;39(3):238-47. PMID: 11867975; doi: 10.1067/mem.2002.121523.
Hastings SN, Schmader KE, Sloane RJ, et al. Adverse health outcomes after discharge from the emergency department--incidence and risk factors in a veteran population. J Gen Intern Med. 2007;22(11):1527-31. PMID: 17828432; doi: 10.1007/s11606-007-0343-9.
McCusker J, Cardin S, Bellavance F, Belzile E. Return to the emergency department among elders: patterns and predictors. Acad Emerg Med. 2000;7(3):249-59. PMID: 10730832; doi: 10.1111/j.1553-2712.2000.tb01070.x.
McCusker J, Healey E, Bellavance F, Connolly B. Predictors of repeat emergency department visits by elders. Acad Emerg Med. 1997;4(6):581-8. PMID: 9189191; doi: 10.1111/j.1553-2712.1997.tb03582.x.
Peters ML. The older adult in the emergency department: aging and atypical illness presentation. J Emerg Nurs. 2010;36(1):29-34. PMID: 20109775; doi: 10.1016/j.jen.2009.06.014.
Grief CL. Patterns of ED use and perceptions of the elderly regarding their emergency care: a synthesis of recent research. J Emerg Nurs. 2003;29(2):122-6. PMID: 12660693; doi: 10.1067/men.2003.65.
McNamara RM, Rousseau E, Sanders AB. Geriatric emergency medicine: a survey of practicing emergency physicians. Ann Emerg Med. 1992;21(7):796-801. PMID: 1610035; doi: 10.1016/s0196-0644(05)81024-8.
Caterino JM, Stevenson KB. Disagreement between emergency physician and inpatient physician diagnosis of infection in older adults admitted from the emergency department. Acad Emerg Med. 2012;19(8):908-15. PMID: 22849819; doi: 10.1111/j.1553-2712.2012.01415.x.
Thomas DR, Tariq SH, Makhdomm S, Haddad R, Moinuddin A. Physician misdiagnosis of dehydration in older adults. J Am Med Dir Assoc. 2003;4(5):251-4. PMID: 12959652; doi: 10.1097/01.JAM.0000083444.46985.16.
Schiff GD, Hasan O, Kim S, et al. Diagnostic error in medicine: analysis of 583 physician-reported errors. Arch Intern Med. 2009;169(20):1881-7. PMID: 19901140; doi: 10.1001/archinternmed.2009.333.
Johnson T, McNutt R, Odwazny R, Patel D, Baker S. Discrepancy between admission and discharge diagnoses as a predictor of hospital length of stay. J Hosp Med. 2009;4(4):234-9. PMID: 19388065; doi: 10.1002/jhm.453.
McCaig LF, McLemore T. Plan and operation of the National Hospital Ambulatory Medical Survey. Series 1: programs and collection procedures. Vital Health Stat 1. 1994;(34):1-78. PMID: 7975355.
Cowen ME, Dusseau DJ, Toth BG, et al. Casemix adjustment of managed care claims data using the clinical classification for health policy research method. Med Care. 1998;36(7):1108-13. PMID: 9674627; doi: 10.1097/00005650-199807000-00016.
Leske MC, Sorensen AA, Zimmer JG. Discrepancies between admission and discharge diagnoses in a university hospital. Med Care. 1978;16(9):740-8. PMID: 682708; doi: 10.1097/00005650-197809000-00004.
McCaig LF, Burt CW. Understanding and interpreting the National Hospital Ambulatory Medical Care Survey: key questions and answers. Ann Emerg Med. 2012;60(6):716-721.e1. PMID: 23083968; doi: 10.1016/j.annemergmed.2012.07.010.
Graber ML. The incidence of diagnostic error in medicine. BMJ Qual Saf. 2013;22 Suppl 2:ii21-ii27. PMID: 23771902; doi: 10.1136/bmjqs-2012-001615.
Minue S, Bermúdez-Tamayo C, Fernández A, et al. Identification of factors associated with diagnostic error in primary care. BMC Fam Pract. 2014;15:92. PMID: 24884984; doi: 10.1186/1471-2296-15-92.
van Duin D. Diagnostic challenges and opportunities in older adults with infectious diseases. Clinical Infect Dis. 2012;54(7):973-8. PMID: 22186775; doi: 10.1093/cid/cir927.
Ely JW, Kaldjian LC, D'Alessandro DM. Diagnostic errors in primary care: lessons learned. J Am Board Fam Med. 2012;25(1):87-97. PMID: 22218629; doi: 10.3122/jabfm.2012.01.110174.
Singh H, Giardina TD, Meyer AN, et al. Types and origins of diagnostic errors in primary care settings. JAMA Intern Med. 2013;173(6):418-25. PMID: 23440149; doi: 10.1001/jamainternmed.2013.2777.
Wilson M, Welch J, Schuur J, O'Laughlin K, Cutler D. Hospital and emergency department factors associated with variations in missed diagnosis and costs for patients age 65 years and older with acute myocardial infarction who present to emergency departments. Acad Emerg Med. 2014;21(10):1101-8. PMID: 25308132; doi: 10.1111/acem.12486.
Chellis M, Olson J, Augustine J, Hamilton G. Evaluation of missed diagnoses for patients admitted from the emergency department. Acad Emerg Med. 2001;8(2):125-30. PMID: 11157287; doi: 10.1111/j.1553-2712.2001.tb01276.x.
Gandhi TK, Kachalia A, Thomas EJ, et al. Missed and delayed diagnoses in the ambulatory setting: a study of closed malpractice claims. Ann Intern Med. 2006;145(7):488-96. PMID: 17015866; doi: 10.7326/0003-4819-145-7-200610030-00006.
Kirch W, Schafii C. Misdiagnosis at a university hospital in 4 medical eras. Medicine (Baltimore). 1996;75(1):29-40. PMID: 8569468; doi: 10.1097/00005792-199601000-00004.
Ilgen JS, Bowen JL, Yarris LM, et al. Adjusting our lens: can developmental differences in diagnostic reasoning be harnessed to improve health professional and trainee assessment? Acad Emerg Med. 2011;18 Suppl 2:S79-86. PMID: 21999563; doi: 10.1111/j.1553-2712.2011.01182.x.
Wang HE, Shah MN, Allman RM, Kilgore M. Emergency department visits by nursing home residents in the United States. J Am Geriatr Soc. 2011;59(10):1864-72. PMID: 22091500; doi: 10.1111/j.1532-5415.2011.03587.x.
Burke RE, Rooks SP, Levy C, et al. Identifying potentially preventable emergency department visits by nursing home residents in the United States. J Am Med Dir Assoc. 2015;16(5):395-9. PMID: 25703449; doi: 10.1016/j.jamda.2015.01.076.
Raven MC, Lowe RA, Maselli J, Hsia RY. Comparison of presenting complaint vs discharge diagnosis for identifying “ nonemergency” emergency department visits. JAMA. 2013;309(11):1145-53. PMID: 23512061; doi: 10.1001/jama.2013.1948.
Leape LL, Brennan TA, Laird N, et al. The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N Engl J Med. 1991;324(6):377-84. PMID: 1824793; doi: 10.1056/NEJM199102073240605.