Antidote availability in the municipality of Campinas, São Paulo, Brazil

Authors

  • Luciane Cristina Rodrigues Fernandes Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas
  • Taís Freire Galvão Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas
  • Adriana Safioti Toledo Ricardi Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas
  • Eduardo Mello De Capitani Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas
  • Stephen Hyslop Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas
  • Fábio Bucaretchi Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

Keywords:

Antidotes, Brazil, Poisoning, Strategic stockpile, Emergency medical services

Abstract

CONTEXT AND OBJECTIVE: The lack of availability of antidotes in emergency services is a worldwide concern. The aim of the present study was to evaluate the availability of antidotes used for treating poisoning in Campinas (SP). DESIGN AND SETTING: This was a cross-sectional study of emergency services in Campinas, conducted in 2010-2012. METHODS: The availability, amount in stock, place of storage and access time for 26 antidotal treatments was investigated. In the hospitals, the availability of at least one complete treatment for a 70 kg adult over the first 24 hours of admission was evaluated based on stock and access recommendations contained in two international guidelines. RESULTS: 14 out of 17 functioning emergency services participated in the study, comprising pre-hospital services such as the public emergency ambulance service (SAMU; n = 1) and public emergency rooms for admissions lasting ≤ 24 hours (UPAs; n = 3), and 10 hospitals with emergency services. Six antidotes (atropine, sodium bicarbonate, diazepam, phytomenadione, flumazenil and calcium gluconate) were stocked in all the services, followed by 13 units that also stocked activated charcoal, naloxone and diphenhydr- amine or biperiden. No service stocked all of the recommended antidotes; only the regional Poison Control Center had stocks close to recommended (22/26 antidotal treatments). The 10 hospitals had almost half of the antidotes for starting treatments, but only one quarter of the antidotes was present with stocks sufficient for providing treatment for 24 hours. CONCLUSION: The stock of antidotes for attending poisoning emergencies in the municipality of Campinas is incomplete and needs to be improved.

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Author Biographies

Luciane Cristina Rodrigues Fernandes, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

RN, MSc. Nurse, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas (Unicamp), Campinas (SP), Brazil.

Taís Freire Galvão, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

BPharm, MSc, PhD. Professor, School of Pharmaceutical Sciences, Universidade Estadual de Campinas (Unicamp), Campinas (SP), Brazil, and Professor, Postgraduate Pharmaceutical Sciences Program, Universidade Federal do Amazonas (UFAM), Manaus (AM), Brazil.

Adriana Safioti Toledo Ricardi, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

RN, MSc. Nurse, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas (Unicamp), Campinas (SP), Brazil.

Eduardo Mello De Capitani, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

MD, MSc, PhD. Professor, Campinas Poison Control Center, and Professor, Department of Clinical Medicine, School of Medical Sciences, Universidade Estadual de Campinas (Unicamp), Campinas (SP), Brazil.

Stephen Hyslop, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

BSc, PhD. Professor, Campinas Poison Control Center, and Professor, Department of Pharmacology, School of Medical Sciences, Universidade Estadual de Campinas (Unicamp), Campinas (SP), Brazil.

Fábio Bucaretchi, Campinas Poison Control Center, School of Medical Sciences, Universidade Estadual de Campinas

MD, MSc, PhD. Professor, Campinas Poison Control Center, and Professor, Department of Pediatrics, School of Medical Sciences, Universidade Estadual de Campinas (Unicamp), Campinas (SP), Brazil.

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Published

2017-02-02

How to Cite

1.
Fernandes LCR, Galvão TF, Ricardi AST, Capitani EMD, Hyslop S, Bucaretchi F. Antidote availability in the municipality of Campinas, São Paulo, Brazil. Sao Paulo Med J [Internet]. 2017 Feb. 2 [cited 2026 May 12];135(1):15-22. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/720

Issue

Vol. 135 No. 1 (2017)

Section

Original Article

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