Congenital papillomas and papillomatoses associated with the Human Papilloma Virus (HPV)
report on 5 cases
Palavras-chave:
Congenital Papilloma, HPV, PapillomatosisResumo
INTRODUÇÃO: Os autores apresentam um estudo de cinco casos de papilomas e papilomatoses vulvares congênitas em neo e nati-mortos. MATERIAL E MÉTODOS: O material utilizado foi proveniente de cinco necrópsias. A avaliação histopatológica mostrou aspectos sugestivos de infecção pelo Pailomavirus humano (HPV). A microscopia eletrônica de três dos casos identificou partículas viróticas nucleares e citoplasmáticas variando de 40 a 60 nm, compatíveis com HPV. RESULTADOS: O estudo imunohistoquímico destas lesões demonstrou imunopositividade citoplasmática e nuclear. CONCLUSÃO: Os autores concluíram que a presença de partículas viróticas somada a imunopositividade em células escamosas, são evidências do provável envolvimento etiológico do HPV nestas lesões.
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