Acute efects of the Paulinia cupana, "Guaraná" on the cognition of normal volunteers
Keywords:
, cognition, sleep, anxietyAbstract
The authors studied the acute effects of "Guaraná", when compared to caffeine and placebo, (double blind study) on cognition, anxiety and sleep in 30 normal volunteers. Although results were negative it cannot be concluded that "Guaraná" is harmless. Other studies shall be undertaken, administering "Guaraná" on a long term basis, as popularly proclaimed.
Downloads
References
ATKINSON, R.C. & SHIFFRIN, R.M. - The control of short-term memory. Scient Amer, 225:82-90, 1971.
BARANOV, A.I. - Medical uses of ginseng and related plants in the Soviet Union: recent trends in the Soviet literature. J Ethnopharmacol, 6:339-353, 1982.
BENOWITZ, N.L. - Clinical pharmacology of caffeine. Ann Rev Med, 41:277-288. 1990.
CARLINI, E.A.; BRAZ, S.; TRONCONI, L.R.P.; TUFIK, S.: ROMANACH, A.K.; PUSTIGLIONE, M.; SPSATAI, M.C.; CUDIZIO, O. & PRADO, N.LA. - Efeito hipnótico de medicação homeopática e do placebo. Avaliação pela técnica de "duplo-cego" e "cruzamento". Rev Ass Med Bra, 33:83-88. 1987.
CARLINI, E.A. - Efeito adptógeno ou resistógeno de algumas plantas. Em: Buchillet, D. Medicinas Tradicionais e Medicina Occidental na Amazônia. MPEG/CNPq/SCT/CEJUP/UEP, Belém, 1991.
CROOK, T.H.; LANABE, G.J. & YOUNGJOHN, J.R. - Diagnosis and assessment of age-associate memory impairment. Clin Neuropharmacol, 13:581-591, 1990.
DILLER, L. (1974)-In neuropsychological Assessment, Muriel D. Lezak - Second Edidion - Oxford University Press, 1983.
ERBER, J.T. (1981) In neuropsychological assessment, Muriel D. Lezak - Second Edition - Oxford University Press, 1983.
FULDER, S - The root of being. Ginseng and the pharmacology of harmony. Hutchinson & Co., London, 1980 a.
FULDER, S. - The drug builds Russians. New Scientist, 87:575-579, 1980 .b.
GLOSSER, G. - In: Lezark, M.D. Neuropsychological assessment - Second Edition - Oxford University Press, New York, 1983.
HAFNER, H.; MOSCHEL, G. & SARTORIUS, N. - Mental health in the elderly. A review of the present state o research. Springer-Verlag Berlin Heidelberg, 1986.
HENMAN, A. - Vida Natural - O Guaraná: sua cultura, propriedades, formas de preparação e uso. Ed Global/Ground, 2º Edição, 1986.
JOHNSON, L.C.; SPINWEBER, C.L. & GOMEZ, S.A.- Benzo diazepines and caffeine: effect on daytime sleepiness, performance, and mood. Psychopharmacology 101:160-167, 1990.
LEZAK, M.D. - Neuropsychological assessment. Oxford University Press (eds) New York, 1983.
NAZARIO, M. - Guaraná - a energia da floresta. Saúde, 6: 40-51, 1989.
PIO CORRÊA, M. - Dicionário das plantas úteis do Brasil e das exóticas cultivadas. Vol, III. Ed. Ministério da Agricultura (IBDF), 1984.
SARTORI, V.A.; ANDREATINI, R. & LEITE, J.R. - Ansiolytic effect of carbamezepine in experimentally - induced anxiety. J Drug Dev, 5(4):251-254, 1993.
SEABRA, M.L.V. & SILVA, E.A. - Avaliação cognitiva de dependentes de álcool e outras drogas psicoativas. Em: Rormigoni, M.L.O.S.; A intervenção breve na dependência de drogas - A experiência brasileira. Ed Contexto - São Paulo, 1992.
SPIELBERGER, C.D., GORSUCH, R.L. & LUSHENE, R.E. - Manual for state - Trait anxiety inventory ("self-evaluation questionnaire"), California, Consulting Psychologists Press, 1970.
WECHSLER, D.A. - A standardized memory scale for clinical use. ,J Psychol, 19:87-95, 1945.