Ileal perineurioma as a cause of intussusception
Keywords:
Ileum, Immunohistochemistry, Nerve sheath neoplasms, Gastrointestinal tract, IntussusceptionAbstract
CONTEXT: Perineuriomas are rare tumors composed of cells resembling those of the normal perineurium. It usually occurs in subcutaneous, softtissue or intraneural locations. Very few reports in the literature have described perineuriomas in the gastrointestinal tract, including the stomach, colon and jejunum. CASE REPORT: We report the clinicopathological and immunohistochemical features of a case of ileal perineurioma that was manifested clinically as intestinal obstruction due to intussusception. Ileal perineurioma has not previously been reported at this anatomical location.
Downloads
References
Lazarus SS, Trombetta LD. Ultrastructural identification of a benign perineurial cell tumor. Cancer. 1978;41(5):1823-9.
Fetsch JF, Miettinen M. Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissue lesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol. 1997;21(12):1433-42.
Kahn DG, Duckett T, Bhuta SM. Perineurioma of the kidney. Report of a case with his- tologic, immunohistochemical, and ultrastructural studies. Arch Pathol Lab Med. 1993;117(6):654-7.
Fagerli JC, Hasegawa SL, Schneck FX. Paratesticular perineurioma: initial description. J Urol. 1999;162(3 Pt 1):881-2.
Hornick JL, Fletcher CD. Intestinal perineuriomas: clinicopathologic definition of a new ana- tomic subset in a series of 10 cases. Am J Surg Pathol. 2005;29(7):859-65.
Agaimy A, Wuensch PH. Perineurioma of the stomach. A rare spindle cell neoplasm that should be distinguished from gastrointestinal stromal tumor. Pathol Res Pract. 2005;201(6):463-7.
Chetty R. Myxoid perineurioma presenting as a gastric polyp. Ann Diagn Pathol. 2010;14(2):125-8.
Agaimy A, Märkl B, Kitz J, et al. Peripheral nerve sheath tumors of the gastrointestinal tract: a multicenter study of 58 patients including NF1-associated gastric schwannoma and unu- sual morphologic variants. Virchows Arch. 2010;456(4):411-22.
Kelesidis T, Tarbox A, Lopez M, Aish L. Perineurioma of esophagus: a first case report. Am J Med Sci. 2009;338(3):230-2.
Emanuel P, Pertsemlidis DS, Gordon R, Xu R. Benign hybrid perineurioma-schwannoma in the colon. A case report. Ann Diagn Pathol. 2006;10(6):367-70.
Hornick JL, Fletcher CD. Soft tissue perineurioma: clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol. 2005;29(7):845-58.
Ariza A, Bilbao JM, Rosai J. Immunohistochemical detection of epithelial membrane antigen in normal perineurial cells and perineurioma. Am J Surg Pathol. 1988;12(9):678-83.
Theaker JM, Gatter KC, Puddle J. Epithelial membrane antigen expression by the perineurium of peripheral nerve and in peripheral nerve tumours. Histopathology. 1988;13(2):171-9.
