Kikuchi-Fujimoto disease

three case reports

Authors

  • Alexandre de Andrade Sousa Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais
  • João Marcos Arantes Soares Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais
  • Marco Homero de Sá Santos Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais
  • Marcelo Portes Rocha Martins Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais
  • José Maria Porcaro Salles Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais

Keywords:

Kikuchi disease, Histiocytic necrotizing lymphadenitis, Lymphatic diseases, Neck, Lymph nodes

Abstract

CONTEXT: Kikuchi-Fujimoto disease (KFD) manifests in most cases as unilateral cervical lymphadenomegaly, with or without accompanying fever. The disease mainly affects young women and has a self-limited course. It is more common in oriental countries, with few reports of its occurrence in Brazil. KFD should be included in the differential diagnosis of suspected cases of viral infections, tuberculosis, reactive lymphadenitis, systemic lupus erythematosus and metastatic diseases. It can be histologically confused with lymphoma. The disease is benign and self-limiting and an excisional biopsy of an affected lymph node is necessary for diagnosis. There is no specific therapy. CASE REPORTS: This study reports on three cases of non-Asian female patients with KFD who were attended at our service between 2003 and 2006. A review of the literature was carried out, with a systematic search on this topic, with the aim of informing physicians about this entity that is manifested by cervical masses and fever.

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Author Biographies

Alexandre de Andrade Sousa, Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais

MD. Surgeon in the Head and Neck Group, Instituto Alfa de Gastroenterologia (IAG), Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.

João Marcos Arantes Soares, Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais

PhD. Surgeon in the Head and Neck Group, Instituto Alfa de Gastroenterologia (IAG), Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.

Marco Homero de Sá Santos, Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais

MD. Resident in Head and Neck Surgery, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.

Marcelo Portes Rocha Martins, Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais

MD. Resident in General Surgery, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.

José Maria Porcaro Salles, Instituto Alfa de Gastroenterologia, Hospital das Clínicas, Universidade Federal de Minas Gerais

MD. Professor of Head and Neck Surgery, Universidade Federal de Minas Gerais (UFMG), and Head of the Head and Neck Group, Instituto Alfa de Gastroenterologia (IAG), Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.

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Published

2010-07-07

How to Cite

1.
Sousa A de A, Soares JMA, Santos MH de S, Martins MPR, Salles JMP. Kikuchi-Fujimoto disease: three case reports. Sao Paulo Med J [Internet]. 2010 Jul. 7 [cited 2025 Oct. 16];128(4):232-5. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/1793

Issue

Vol. 128 No. 4 (2010)

Section

Case Report

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