Hemosiderotic fibrohistiocytic lipomatous lesion

case report and review of the literature

Authors

  • Antônio Roberto Oliveira Ramalho Universidade Federal do Triângulo Mineiro
  • Marcella Nara Nunes Universidade Federal do Triângulo Mineiro
  • Sheila Jorge Adad Universidade Federal do Triângulo Mineiro
  • Sebastião Almeida Leitão Universidade Federal do Triângulo Mineiro
  • Adilha Misson Rua Micheletti Universidade Federal do Triângulo Mineiro

Keywords:

Hemosiderin, Histiocytes, Soft tissue neoplasms, Lipoma, Venous insufficiency

Abstract

CONTEXT: Lesions of the adipose tissue are the most common type of soft-tissue lesion among adults. CASE REPORT: We describe the case of a 33-year-old female patient with a soft-tissue lesion in her left knee that was diagnosed as a hemosiderotic fibrohistiocytic lipomatous lesion. This type of lesion, which was described for the first time in 2000, preferentially affects the ankle region of middle-aged women with a history of previous local trauma. Lesion recurrence is common, caused by incomplete resection, although there have not yet been any reports of metastases. After a review of the literature, we describe the clinical, radiological, morphological and immunohistochemical characteristics, along with their main differential diagnoses.

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Author Biographies

Antônio Roberto Oliveira Ramalho, Universidade Federal do Triângulo Mineiro

MD. Pathology resident, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.

Marcella Nara Nunes, Universidade Federal do Triângulo Mineiro

Medical student, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.

Sheila Jorge Adad, Universidade Federal do Triângulo Mineiro

PhD. Associate professor, Discipline of Special Pathology, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.

Sebastião Almeida Leitão, Universidade Federal do Triângulo Mineiro

MD. Adjunct professor, Discipline of Orthopedics, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.

Adilha Misson Rua Micheletti, Universidade Federal do Triângulo Mineiro

PhD.Adjunct professor, Discipline of Special Pathology, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.

References

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Kazakov DV, Sima R, Michal M. Hemosiderotic fibrohistiocytic lipomatous lesion: clinical correlation with venous stasis. Virchows Arch. 2005;447(1):103-6.

Browne TJ, Fletcher CD. Haemosiderotic fibrolipomatous tumour (so-called haemosiderotic fibrohistiocytic lipomatous tumour): analysis of 13 new cases in support of a distinct entity. Histopathology. 2006;48(4):453-61.

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Published

2009-05-05

How to Cite

1.
Ramalho ARO, Nunes MN, Adad SJ, Leitão SA, Micheletti AMR. Hemosiderotic fibrohistiocytic lipomatous lesion: case report and review of the literature. Sao Paulo Med J [Internet]. 2009 May 5 [cited 2025 Mar. 14];127(3):174-6. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/1872

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Section

Case Report