Ultrastructural aspects of the remodeling process of the Corpus albicans in the recent postmenopausal period

Authors

  • Gustavo Rubino de Azevedo Focchi Universidade Federal de São Paulo
  • Manuel de Jesus Simões Universidade Federal de São Paulo
  • Edmund Chada Baracat Universidade Federal de São Paulo
  • Geraldo Rodrigues de Lima Universidade Federal de São Paulo
  • Joaquim Evêncio Neto Universidade Federal de São Paulo

Keywords:

Corpus albicans, Menopause, Ultrastructure, Cytophysiology, Remodeling process

Abstract

To study the cytophysiology of the Corpus albicans in the recent postmenopausal period, the authors analyzed the ovarian ultrastructure of ten patients submitted to oophorectomy due to non-malignant gynecological diseases. Evidence of a remodeling process with connective tissue substitution of the corpora albicantia was observed. The remodeling process appears to depend on the activity of three essential cell types: the fibroblasts, which provide collagen synthesis; the macrophages, which phagocytize the flaky material; and the myofibroblasts, mainly located in the peripheral region of the corpora albicantia, which may have a retracting action on the remodeling site of the Corpus albicans.

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Author Biographies

Gustavo Rubino de Azevedo Focchi, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Morphology, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Manuel de Jesus Simões, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Morphology, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Edmund Chada Baracat, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Morphology, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Geraldo Rodrigues de Lima, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Morphology, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Obstetrics and Gynecology, São Paulo, Brazil.

Joaquim Evêncio Neto, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Morphology, São Paulo, São Paulo, Brazil. Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Obstetrics and Gynecology, São Paulo, Brazil.

References

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Published

1996-05-05

How to Cite

1.
Focchi GR de A, Simões M de J, Baracat EC, Lima GR de, Evêncio Neto J. Ultrastructural aspects of the remodeling process of the Corpus albicans in the recent postmenopausal period. Sao Paulo Med J [Internet]. 1996 May 5 [cited 2025 Oct. 16];114(3):1173-6. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/1995

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Section

Review and Updating