Neurological examination in obsessive-compulsive disorder

Authors

  • Paulo Caramelli Universidade de São Paulo; University of Montréal
  • Mauro Aranha de Lima Universidade de São Paulo; University of Montréal
  • Emmanuel Stip Universidade de São Paulo; University of Montréal
  • Luiz Alberto Bacheschi Universidade de São Paulo; University of Montréal

Keywords:

Obsessive-Compulsive Disorder, Neurological examination, Clomipramine

Abstract

Recent studies suggest the occurrence of a neurological dysfunction in Obsessive-Compulsive Disorder (OCD). The purpose of the present study was to verify the clinical value of a neurological evaluation in patients with the disease. We submitted 15 patients with OCD (five of whom were under clomipramine) and 15 controls in a detailed neurological examination, including assessment of the neurological soft-signs. Eleven patients (73.3 percent) and four controls (26.7 percent) presented abnormalities on examination. The main findings among the patients were: palmomental reflex (six cases); mirror movements (five cases); agraphestesia and dysdiadochokinesia (three cases). Three out of the four patients who had a normal examination were on clomipramine. Palmomental reflex was the main finding among the controls. These results, although preliminary, stress the interest and usefulness of performing a detailed neurological examination in OCD.

Downloads

Download data is not yet available.

Author Biographies

Paulo Caramelli, Universidade de São Paulo; University of Montréal

Universidade de São Paulo, School of Medicine, Department of Psychiatry, São Paulo, São Paulo, Brazil. Universidade de São Paulo, School of Medicine, Department of Neurology, São Paulo, Brazil. University of Montréal, Department of Psychiatry, Montréal, Canada.

Mauro Aranha de Lima, Universidade de São Paulo; University of Montréal

Universidade de São Paulo, School of Medicine, Department of Psychiatry, São Paulo, São Paulo, Brazil. Universidade de São Paulo, School of Medicine, Department of Neurology, São Paulo, Brazil. University of Montréal, Department of Psychiatry, Montréal, Canada.

Emmanuel Stip, Universidade de São Paulo; University of Montréal

Universidade de São Paulo, School of Medicine, Department of Psychiatry, São Paulo, São Paulo, Brazil. Universidade de São Paulo, School of Medicine, Department of Neurology, São Paulo, Brazil. University of Montréal, Department of Psychiatry, Montréal, Canada.

Luiz Alberto Bacheschi, Universidade de São Paulo; University of Montréal

Universidade de São Paulo, School of Medicine, Department of Psychiatry, São Paulo, São Paulo, Brazil. Universidade de São Paulo, School of Medicine, Department of Neurology, São Paulo, Brazil. University of Montréal, Department of Psychiatry, Montréal, Canada.

References

George MS, Melvin JA, Kellner CH. Obsessive-compulsive symptoms in neurologic disease: a review. Behavioural Neurology 1992;5:3-10.

Kettl PA, Marks IM. Neurological factors in Obsessive-Compulsive Disorder. Two case reports and a review of the literature. Br J Psychiat 1986;149:315-9.

Baxter LR, Schwartz JM, Mazziota JC, et al. Cerebral glucose metabolic rates in nondepressed patients with Obsessive-Compulsive Disorder. Am J Psychiatry 1988;145:1560-3.

Insel TR. Toward a neuroanatomy of Obsessive-Compulsive Disorder. Arch Gen Psychiatry 1992;49:739-44.

Swedo SE, Schapiro MB, Grady CL, et al. Cerebral glucose metabolism in childhood-onset Obsessive-Compulsive Disorder. Arch Gen Psychiatry 1989;46:518-23.

Hollander E, Schiffman E, Cohen B, et al. Signs of central nervous system dysfunction in Obsessive-Compulsive Disorder. Arch Gen Psychiatry 1990;47:27-32.

Baxter LR, Schwartz JM, Bergman KS, et al. Caudate glucose metabolism rate changes with both drug and behavior therapy for Obsessive-Compulsive Disorder. Arch Gen Psychiatry 1992;49:681-9.

Swedo SE, Pietrini P, Leonard HL, et al. Cerebral glucose metabolism in childhood-onset Obsessive-Compulsive Disorder. Revisualization during pharmacotherapy. Arch Gen Psychiatry 1992;49:690-4.

Christensen KJ, Kim SW, Dysken MW, et al. Neuropsychological performance in Obsessive-Compulsive Disorder. Biol Psychiatry 1992;31:4-18.

Laplane D, Levasseur M, Pillon B, et al. Obsessive-compulsive and other behavioural changes with bilateral basal ganglia lesions. A neuropsychological, magnetic resonance imaging and positron tomography study. Brain 1989;112:699-725.

Jacobs L, Gossman MD. Three primitive reflexes in normal adults. Neurology 1980;30:184-8.

Downloads

Published

1996-09-09

How to Cite

1.
Caramelli P, Lima MA de, Stip E, Bacheschi LA. Neurological examination in obsessive-compulsive disorder. Sao Paulo Med J [Internet]. 1996 Sep. 9 [cited 2025 Oct. 16];114(5):1255-8. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2043

Issue

Section

Original Article