Primary mucinous adenocarcinoma of the bladder with signet-ring cells

case report

Authors

  • Marcelo Lorenzi Marques Hospital Professor Edmundo Vasconcelos
  • Gabriel Salum D’Alessandro Hospital Professor Edmundo Vasconcelos
  • Daher Cezar Chade Hospital Professor Edmundo Vasconcelos
  • Valéria Pereira Lanzoni Hospital Professor Edmundo Vasconcelos
  • Samuel Saiovici Hospital Professor Edmundo Vasconcelos
  • Cláudio José Ramos de Almeida Hospital Professor Edmundo Vasconcelos

Keywords:

Urinary bladder, Urinary bladder neoplasms, Mucinous adenocarcinoma, Immunohistochemistry, Signet ring cell carcinoma

Abstract

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often diffi cult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confi rmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

Downloads

Download data is not yet available.

Author Biographies

Marcelo Lorenzi Marques, Hospital Professor Edmundo Vasconcelos

MD. Resident, Urology Service, Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.

Gabriel Salum D’Alessandro, Hospital Professor Edmundo Vasconcelos

MD. Resident, General Surgery, Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.

Daher Cezar Chade, Hospital Professor Edmundo Vasconcelos

MD. Resident, Urology Service, Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.

Valéria Pereira Lanzoni, Hospital Professor Edmundo Vasconcelos

MD. Attending physician, Pathology Service, Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.

Samuel Saiovici, Hospital Professor Edmundo Vasconcelos

MD. Attending physician, Urology Service, Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.

Cláudio José Ramos de Almeida, Hospital Professor Edmundo Vasconcelos

MD. Head of the Urology Service, Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.

References

Zaghloul MS, Nouh A, Nazmy M, et al. Long-term results of primary adenocarcinoma of the urinary bladder: a report on 192 patients. Urol Oncol. 2006;24(1):13-20.

Fiter L, Gimeno F, Martin L, Gómez Tejeda L. Signet-ring cell adenocarcinoma of bladder. Urology. 1993;41(1):30-3.

Wang HL, Lu DW, Yerian LM, et al. Immunohistochemical distinc- tion between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Am J Surg Pathol. 2001;25(11):1380-7.

Torenbeek R, Lagendijk JH, Van Diest PJ, Bril H, van de Molengraft FJ, Meijer CJ. Value of a panel of antibodies to identify the primary origin of adenocarcinomas presenting as bladder carcinoma. Histopathology. 1998;32(1):20-7.

Lau SK, Weiss LM, Chu PG. Differential expression of MUC1, MUC2, and MUC5AC in carcinomas of various sites: an immunohistochemical study. Am J Clin Pathol. 2004;122(1):61-9.

Downloads

Published

2007-09-09

How to Cite

1.
Marques ML, D’Alessandro GS, Chade DC, Lanzoni VP, Saiovici S, Almeida CJR de. Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report. Sao Paulo Med J [Internet]. 2007 Sep. 9 [cited 2025 Oct. 16];125(5):297-9. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2149

Issue

Section

Case Report