Verrucous carcinoma of the bladder with koilocytosis unassociated with vesical schistosomiasis

Authors

  • Fabio Lewin Faculdade de Medicina do ABC
  • Ana Paula Garcia Cardoso Faculdade de Medicina do ABC
  • Lucíla Heloísa Simardi Faculdade de Medicina do ABC
  • Marcos Tobias Machado Faculdade de Medicina do ABC

Keywords:

Verrucous carcinoma, Bladder, Schistosomiasis, Human papillomavirus

Abstract

CONTEXT: Verrucous carcinoma of the bladder is a very rare malignant neoplasm, histologically similar to condyloma acuminatum. Usually it shows association with vesical schistosomiasis (bilharziasis). Only 13 cases unrelated to bilharziasis have been reported to date, and none of them reported koilocytosis, a typical finding in human papillomavirus infection. CASE REPORT: We report a case of verrucous carcinoma of the bladder that was unrelated to bilharziasis, with koilocytosis and absence of human papillomavirus. The literature relating to the topic is discussed.

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Author Biographies

Fabio Lewin, Faculdade de Medicina do ABC

Fifth year medical student, Faculdade de Medicina do ABC, São Paulo, Brazil.

Ana Paula Garcia Cardoso, Faculdade de Medicina do ABC

Fifth year medical student, Faculdade de Medicina do ABC, São Paulo, Brazil.

Lucíla Heloísa Simardi, Faculdade de Medicina do ABC

MD, PhD. Professor, Discipline of Pathology, Faculdade de Medicina do ABC, São Paulo, Brazil.

Marcos Tobias Machado, Faculdade de Medicina do ABC

Assistant Professor of the Discipline of Urology (Tumor Group), Faculdade de Medicina do ABC, São Paulo, Brazil.

References

El-Bolkainy MN, Mokhtar NM, Ghoneim MA, Hussein MH. The impact of schistosomiasis on the pathology of bladder car- cinoma. Cancer. 1981;48(12):2643-8.

Ackerman LV. Verrucous carcinoma of the oral cavity. Sur- gery. 1948;23:670-8.

el-Sebai I, Sherif M, el-Bolkainy MN, Mansour MA, Ghoneim MA. Verrucose squamous carcinoma of bladder. Urology. 1974;4(4):407-10.

Cheng L, Leibovich BC, Cheville JC, et al. Squamous papilloma of the urinary tract is unrelated to condyloma acuminata. Cancer. 2000;88(7):1679-86.

Batta AG, Engen DE, Reiman HM, Winkelmann RK. Intra- vesical condyloma acuminatum with progression to verrucous carcinoma. Urology. 1990;36(5):457-64.

Pinto AC, Pompeo ACL, Arap S. Condiloma acuminado de bexiga. J Bras Urol. 1998;24:272-3.

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Published

2004-03-03

How to Cite

1.
Lewin F, Cardoso APG, Simardi LH, Machado MT. Verrucous carcinoma of the bladder with koilocytosis unassociated with vesical schistosomiasis. Sao Paulo Med J [Internet]. 2004 Mar. 3 [cited 2025 Oct. 16];122(2):64-6. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2489

Issue

Section

Case Report