Cystic struma ovarii
a rare presentation of an infrequent tumor
Keywords:
Cystic struma ovarii, Frozen section, TeratomaAbstract
CONTEXT: Struma ovarii, a rare neoplasm, is a monophyletic teratoma composed of thyroid tissue. It is generally considered to account for less than 5% of mature teratomas. CASE REPORT: A diagnosis of struma ovarii may be the source of many diagnostic problems. It may be cystic and microscopic examination may only reveal a few typical thyroid follicles, resulting in confusion with other cystic ovarian tumors. Extensive sampling should be undertaken and immunohistochemistry may be decisive in establishing the thyroid nature of the epithelial lining. The authors report two cases of cystic struma ovarii, and discuss diagnostic criteria and the limitations of frozen biopsies in these tumors.
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References
Ayhan A, Yanik F, Tuncer R, et al. Struma ovarii. Int J Gynecol Obstet 1993;42:143.
Szyfelbein WM, Young RH, Scully RE. Cystic struma ovarii: a frequently unrecognized tumor. A report of 20 cases. Am J Surg Pathol 1994;18:785.
Henzen-Logmans SC, Mullink H, Ramaekers FCS, Tadema T, Meyer CJLM. Expression of cytokeratins and vimentin in epithelial cells of normal and pathologic thyroid tissue. Virchows Archiv 1987;410:347.
Rose PG, Rubin RB, Nelson BE, et al. Accuracy of frozen section (intraoperative consultation) diagnosis of ovarian tumors. Am J Obstet Gynecol 1994;171:823.
