Vena cava thrombosis associated with nephrotic syndrome in the puerperal gestational cycle
Keywords:
Nephrotic Syndrome, Puerperium, Pregnancy, Cava thrombosis, ThromboembolismAbstract
CONTEXT: The puerperal gestational cycle is accompanied by a state of physiological hypercoagulability. Thromboembolic phenomena may occur at this time. OBJECTIVE: To report on a clinic case involving a patient that presented a family history of thromboembolism and developed deep vein thrombosis in a lower limb and vena cava thrombosis during the puerperal gestational cycle, displaying nephrotic syndrome as the main complication. DESIGN: Case report.
Downloads
References
Gagnadoux F, Lecalvez JF, Azarian R, Petitpretz R. Facteurs de risque de la maladie thrombo-embolique veineuse. Presse Med 1998;27(17):814-8.
Hooper WC, Evatt BL. The role of activated protein C resistance in the pathogenesis of venous thrombosis. Am J Med Sci 1998;316(2):120-7.
Tijerina GL, Barrientos MA, Gillaumin AS. Deficiencia hereditaria de antitrombina III. Presentación de um caso obstétrico y revisión de la literatura. Ginecol Obstet México 1996;64:177-83.
Cerneca F, Ricci G, Simeone R, Malisano M, Alberico S, Guaschino S. Coagulation and fibrinolysis in normal pregnancy. Increased lev- els of procoagulants and reduced levels of inhibitors during pregnancy induce a hypercoagulable state, combined with a reactive fibrinolysis. Eur J Obstet Gynecol Reprod Biol 1997;73:31-4.
Hallak M, Senderowicz J, Cassel A, et al. Activated protein C resistance (factor V Leiden) associated with thrombosis in preg- nancy. Am J Obstet Gynecol 1997;176(4):889-93.
Middeldorp S, Henkens CMA, et al. The incidence of venous thromboembolism in family members of patients with factor V Leiden mutation and venous thrombosis. Ann Intern Med 1998;128(1):15-20.
Grandone E, Margaglione M, et al. Genetic susceptibility to preg- nancy-related venous thromboembolism. Role of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations. Am J Obstet Gynecol 1998;179(5):1324-8.
Rosendaal FR. Venous Thrombosis: a multicausal disease. Lancet 1999;353(3):1167-73.
De Stefano V, Finazzi G, Manucci PM. Inherited thrombophilia: pathogenesis, clinical syndromes and management. Blood 1996; 9(1):3531-44.
Gladman DD, Urowitz MB. Systemic lupus erythematosus. In: Klipplel JH, Dieppe PA, editors. Rheumatology. London: Mosby; 1994:6(2.1-2.20).
Bick RL, Ancypa D, McIntyre KJ. Understanding the antiphospholipid thrombosis syndromes. Laboratory Med 1995;26(2):124-30.
Alarcón-Segovia D. Clinical manifestation of the antiphospholipid syndrome. J Rheumatol 1992;19(11):1778-81.
Hughes GRV. The antiphospholipid syndrome: ten years on. Lan- cet 1993;342:341-4.
Greer IA. Thrombosis in pregnancy: maternal and fetal issues. Lancet 1999;353(10):1258-65.