Vena cava thrombosis associated with nephrotic syndrome in the puerperal gestational cycle

Authors

  • Maíta Poli Araújo Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • Carla Gonçalves Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • Roberta Gonçalves Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • José Wilson Ramos Braga Júnior Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • Thaís Vilela Peterson Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • Álvaro Nagib Atallah Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • Emília Inoue Sato Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro
  • Virgínia Fernandes Moça Trevisani Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

Keywords:

Nephrotic Syndrome, Puerperium, Pregnancy, Cava thrombosis, Thromboembolism

Abstract

CONTEXT: The puerperal gestational cycle is accompanied by a state of physiological hypercoagulability. Thromboembolic phenomena may occur at this time. OBJECTIVE: To report on a clinic case involving a patient that presented a family history of thromboembolism and developed deep vein thrombosis in a lower limb and vena cava thrombosis during the puerperal gestational cycle, displaying nephrotic syndrome as the main complication. DESIGN: Case report.

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Author Biographies

Maíta Poli Araújo, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

Undergraduate student, Universidade de Santo Amaro, São Paulo, Brazil.

Carla Gonçalves, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

Undergraduate student, Universidade de Santo Amaro, São Paulo, Brazil.

Roberta Gonçalves, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

Undergraduate student, Universidade de Santo Amaro, São Paulo, Brazil.

José Wilson Ramos Braga Júnior, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

Resident, Discipline of Rheumatology, Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, Brazil.

Thaís Vilela Peterson, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

Undergraduate student, Universidade de Santo Amaro, São Paulo, Brazil.

Álvaro Nagib Atallah, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

MD, PhD, MCE. Head of the Discipline of Urgent Medicine, Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, Brazil.

Emília Inoue Sato, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

MD, PhD, MCE. Titular Professor, Discipline of Rheumatology, Universidade Federal de São Paulo/ Escola Paulista de Medicina, São Paulo, Brazil.

Virgínia Fernandes Moça Trevisani, Universidade Federal de São Paulo/Escola Paulista de Medicina and Universidade de Santo Amaro

MD, PhD. Titular Professor, Discipline of Rheumatology, Universidade de Santo Amaro, UNISA and Acting Professor of the Discipline of Urgent Medicine, Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, Brazil.

References

Gagnadoux F, Lecalvez JF, Azarian R, Petitpretz R. Facteurs de risque de la maladie thrombo-embolique veineuse. Presse Med 1998;27(17):814-8.

Hooper WC, Evatt BL. The role of activated protein C resistance in the pathogenesis of venous thrombosis. Am J Med Sci 1998;316(2):120-7.

Tijerina GL, Barrientos MA, Gillaumin AS. Deficiencia hereditaria de antitrombina III. Presentación de um caso obstétrico y revisión de la literatura. Ginecol Obstet México 1996;64:177-83.

Cerneca F, Ricci G, Simeone R, Malisano M, Alberico S, Guaschino S. Coagulation and fibrinolysis in normal pregnancy. Increased lev- els of procoagulants and reduced levels of inhibitors during pregnancy induce a hypercoagulable state, combined with a reactive fibrinolysis. Eur J Obstet Gynecol Reprod Biol 1997;73:31-4.

Hallak M, Senderowicz J, Cassel A, et al. Activated protein C resistance (factor V Leiden) associated with thrombosis in preg- nancy. Am J Obstet Gynecol 1997;176(4):889-93.

Middeldorp S, Henkens CMA, et al. The incidence of venous thromboembolism in family members of patients with factor V Leiden mutation and venous thrombosis. Ann Intern Med 1998;128(1):15-20.

Grandone E, Margaglione M, et al. Genetic susceptibility to preg- nancy-related venous thromboembolism. Role of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations. Am J Obstet Gynecol 1998;179(5):1324-8.

Rosendaal FR. Venous Thrombosis: a multicausal disease. Lancet 1999;353(3):1167-73.

De Stefano V, Finazzi G, Manucci PM. Inherited thrombophilia: pathogenesis, clinical syndromes and management. Blood 1996; 9(1):3531-44.

Gladman DD, Urowitz MB. Systemic lupus erythematosus. In: Klipplel JH, Dieppe PA, editors. Rheumatology. London: Mosby; 1994:6(2.1-2.20).

Bick RL, Ancypa D, McIntyre KJ. Understanding the antiphospholipid thrombosis syndromes. Laboratory Med 1995;26(2):124-30.

Alarcón-Segovia D. Clinical manifestation of the antiphospholipid syndrome. J Rheumatol 1992;19(11):1778-81.

Hughes GRV. The antiphospholipid syndrome: ten years on. Lan- cet 1993;342:341-4.

Greer IA. Thrombosis in pregnancy: maternal and fetal issues. Lancet 1999;353(10):1258-65.

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Published

2001-01-01

How to Cite

1.
Araújo MP, Gonçalves C, Gonçalves R, Braga Júnior JWR, Peterson TV, Atallah Álvaro N, Sato EI, Trevisani VFM. Vena cava thrombosis associated with nephrotic syndrome in the puerperal gestational cycle. Sao Paulo Med J [Internet]. 2001 Jan. 1 [cited 2025 Mar. 12];119(1):24-8. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2738

Issue

Section

Case Report