The desmoplastic limph node reaction as a prognostic factor of cancer of the tongue and floor of the mouth.
Palavras-chave:
Desmoplasia, Lymph node, Extracapsular spreadResumo
Para determinar o significado do prognóstico da desmoplasia nos linfonodos metastáticos de carcinoma epidermóide da língua oral e do soalho da boca, 37 casos desta doença foram estudados. Desmoplasia estava presente em 59,4% dos casos e associada com rotura capsular em 40,5%. A associação de desmoplasia com envolvimento linfonodal extenso ocorreu em 59,4%. Estas relações foram estatisticamente significantes (p= 0,002 e 0,0069). Os resultados obtidos sugerem que a desmoplasia é um fator associado com mau prognóstico.
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ANASTASSIADES, O. T. & PRYCE, D. M. - Immunological significance of the morphological changes in lymph nodes draining breast cancer. Br J Cancer 20:239- 249, 1966.
ANDERSON, R. E. & WARNER, N. L. - Ionizing radiation and the immune response. Adv Immunol 24:215-235. 1976.
BAKER, R. R.; WOOD, S.; COMP. P. V. & KIM, S. T. et all Role of the cervical lymph nodes as a barrier to metastatic tumor. Am J Surg 118:654-659, 1969.
BENNET, S. H.; FUTRELL, J. W.; ROTH, J. A. & HOYE, R. C. et all - Prognostic significance of histologic host response in cancer of the larynx or hypopharynx. Cancer 28:1255-1265, 1971.
BERLINGER, N. T.; TSAKRAKLIDES, V.; POLLAK. K. & ADAMS, G. L. et all - Immunologic assesment of regional lymph node histology in relation to survival in head and neck carcinoma. Cancer 36:697-705, 1976.
BERLINGER, N. T.; TSAKRAKLIDES, V.; POLLAK, K. & ADAMS, G. L. et all - Prognostic significance of lymph node histology in patients with squamous cell carcinoma o the larynx, pharynx or oral cavity. Laryngoscope 86:792-803, 1976.
BLACK, M. M.: KERPE, S. & SPEER. F. D. - Lymph node structure in patients with cancer of the breast. Am J Path 24:505-521, 1953.
BLACK, M. M.; SPEER, F. D. & OPLER, S. R. - Structural representations of tumor-host relationships in mammary carcinoma. Biologic and Prognostic significance. Am J Clin Pathol 26:250-265, 1956.
BLACK, M. M. & SPEER, F. D. - Sinus histiocytosis of lymphnodes in cancer. Surg Gynecol Obstet 106:163-175, 1958.
BRYNES, R. K.; HUNTER, R. L. & VELLIOS, F. - Immunomorphologic changes in regional lymph nodes associated with cancer. Arch Pathol Lab Med 107:217-221, 1983.
COTTIER,H.; TURK, J. & SOBIN, L. - A proposal for a standardized system of reporting human lymph node morphology in relation to immunological function. J Clin Pathol 26:317-331, 1973.
CRILE, G. - Excision of cancer of the head and neck. With special reference to the plan of dissection based on 132 operations. JAMA 47(22):1780-1786, 1906.
ENGESET, A. - Barrier function of lymph-glands. Lancet 1:324, 1962 (letter).
GRAY, J. H. - The relation of lymphatic vessels to the spread of cancer. Brit J Surg 26:462-495, 1939.
HERMANEK, U. K. & SOBIN, L. H. Ed. - Classification of malignant tumours. 4a ed rev Berlin Springer - Verlag 1987, 197 p.
JANSA, P. & RIEGROV, D. - Prognostic significance of reactive changes in regional lymph nodes in cancer. Acta Univ Palacki Omoluc Fac Med 105:111-120, 1983.
JOHNSON, J. T.; BARNES, E. L.; MYERS, E. N. & SCHRAMM, V. L. et alli. - The extracapsular spread of tumors in cervical node metastases. Arch Otolaryngol 107:725-729. 1981.
JOHNSON, J. T.; MYERS, E. N.; BEDETTI, C. D. & BARNES, E. L. et alli. - Cervical lymph node metastases. Arch Otolaryngol 111:534-537, 1985.
KALNINS, I. K.; LEONARD, A. G.; SAKO, K. & RAZACK, M. S. et al - Correlation between prognosis and degree of lymph node involvement in carcinoma of the oral cavity. Am J Surg 134:450-454, 1977.
NOONE, R. B.; BONNER, Jr.,H.; RAYMOND, S. & BROWN, A. S. et alli - Lymph node metastases in oral carcinoma. A correlation or histopathology with survival. Plas Reconst Surg 53(2):158-166,1974.
OLSEN. K. D.- Tratamento do pescoço na década de 90. Conferência proferida na XXXIV Reunião Anual de Cancerologia do Hospital A. C. Camargo, São Paulo, 1992.
POINTON, R. C. & JELLY, G. O. - Block dissection of the neck for squamous cell carcinoma of the mouth and lips. Proc Roy Soc Med 69:414-416, 1976.
POLLARD, J. H. - A handbook of numerical and statistical techniques. New York Cambridge University Press 1977, 349 p.
SCHULLER, D. E. - An assesment of neck node immunorreactivity in head and neck cancer. Laryngoscope 94(11 Pt. 2 suppl. 35): 1-35, 1984.
TSAKRAKLIDES, V.; ANASTASSIADES, O. T. & KERSEY, J. H.- Prognostic significance of regional lymph node histology in uterine cervical cancer. Cancer 31:860- 868, 1973.
WELSH, L. W. & CAMPELONE, F. - Effects of irradiation of cervical lymph nodes. Ann Otol 88:502-508, 1979.
ZEIDMANN, I. & BUSS, J. M. - Experimental studies on the spread of cancer in the lymphatic system. I.Effectiveness of the lymph node as a barrier to the passage of embolic tumor cells. Cancer Research 14:403-405, 1954.
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