Direct immunofluorescence in Lupus Erythematosus (LE)
Palavras-chave:
Direct immunofluorescence (DIF), Lupus erythematosus (LE), Discoid lupus erythematosus (DLE), Subacute lupus erythematosus (SALE), Systemic lupus erythematosus (SLE), Immunoglobulins (Igs)Resumo
Foram estudados cento e vinte e seis pacientes com LE, distribuídos da seguinte forma: 84 com LED, 13 com LESA e 29 com LES. Foram realizadas biópsias na pele lesada, que foram submetidas a IFD. Houve positividade de 69% para o LED, 61,5% para o LESA e 72,4% para o LES, dados estes que estão de acordo com a literatura. IgM foi a lg mais freqüentemente encontrada, seguida da associação IgM+C3.
Downloads
Referências
Ahmed AR, Provost TT. Incidence of a positive lupus band test using sun-exposed and unexposed skin. Arch Dermatol 1979;115:228-9.
Baart F, Kuyper EH, Cormane RH. The occurrence of certain serum factors in the dermal-epidermal junction and vessel walls of the skin in lupus erythematosus and other skin diseases. Acta Dermatovener 1968;48:578-88.
Blaszczyk M, Dahl MV. Usefulness of direct immunofluorescence in patients with lupus erythematosus. Arch Dermatol 1983;119:1010-7.
Burham TK, Neblett TR, Fine G. The application of the fluorescent antibody technique to the investigation of lupus erythematosus and various dermatoses. J Invest Dermatol 1963;41:451-6.
Cormane RH. "Bound" globulin in the skin of patients with chronic discoid lupus erythematosus and systemic lupus erythematosus. Lancet 1964;1:534-5.
Harrist TJ, Mihm MC. The specificity and clinical usefulness of the lupus band test. Arthritis Rheum 1980;23(4):479-90.
Jordon RE, Schroeter AL, Winkelman RK. Dermal-epidermal deposition of complement components and properdin in systemic lupus erythematosus. Brit J Dermatol 1975;92:263-71.
Monroe EW. Lupus band test. Arch Dermatol 1977;113:830-4.
Nieboer C, Tak-Diamand Z, Van Leeuwen-Wallau HE. Dust-like particles: a specific direct immunofluorescence pattern in sub-acute cutaneous lupus erythematosus. Brit J Dermatol 1988;118:725-34.
Proença NG, Machado ER, Paes RP. Bernardes MP. Reavaliação dos resultados obtidos com a técnica de imunofluorescência direta em lesão de lupus eritematoso discóide. An Bras Dermatol 1985;60:303-6.
Provost TT. Lupus band test. Int J Dermatol 1981;20:475-81.
Ratnam KV, Phay KL, Ng SK, Tan T Skin immunofluorescence patterns in SLE patients in Singapore. Singapore Med J 1987;6:517-9.
Sontheimer RD, Thomas JR, Gilliam JN. Subacute cutaneous lupus erythematosus. Arch Dermatol 1979;115:1409-15.
Sugai AS, Gerbase AB, Cernea SS, et al. Cutaneous lupus erythematosus: direct immunofluorescence and epidermal basal membrane study. Int J Dermatol 1992;31(4):260-4.
Tan EM, Choen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthr and Rheum 1975;25:1271.
Ten Have-Opbraek AAW. Demonstration of immunoglobulin and complement in the skin of patients with lupus erythematosus. Acta Dermatovener 1966;46:68-71.
Tuffanelli DL. Cutaneous immunopathology. Recent observations. J Invest Dermatol 1975;65:143-53.
Tuffanelli DL. Clinical cutaneous immunopathology. J C E Dermatology 1978;16:19-39.
Weingand DA. Cutaneous immunofluorescence. Med Clin of North America 1989;73(5):1263-74.
Downloads
Publicado
Como Citar
Edição
Seção
Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.