Nutrição na insuficiência renal aguda
Palavras-chave:
Insuficiência renal aguda, Nutrição, Avaliação nutricional, Terapia nutricional, MortalidadeResumo
O estado nutricional tem sido considerado como um dos possíveis determinantes da taxa de mortalidade em insuficiência renal aguda. No entanto, na maioria dos estudos que avaliam possíveis preditores de mortalidade na insuficiência renal aguda, pouca atenção tem sido dada ao estado nutricional, possivelmente em função das dificuldades de sua avaliação em pacientes críticos. Embora os métodos tradicionais de avaliação nutricional sejam usados na insuficiência renal aguda, estes não são os mais indicados para esta população de pacientes. O uso de suporte nutricional nestes pacientes tem originado resultados conflitantes em relação à morbidade e à mortalidade. Esta revisão aborda os mecanismos e marcadores de desnutrição na insuficiência renal aguda e os possíveis procedimentos de suporte nutricional a serem realizados.
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Hou SH, Bushinsky DA, Wish JB, Cohen JJ, Harrington JT Hospital-acquired renal insufficiency: a prospective study. Am J Med. 1983;74(2):243-8.
Burdmann EA, Oliveira MB, Ferraboli R, et al. Epidemiologia. In: Schor N, Boim M, Dantos DFP, editores. Insuficiência Renal Aguda: Fisiopatologia, Clínica e Tratamento. 1st. ed. São Paulo: Sarvier; 1997. p. 1-7.
Groeneveld AB, Tran DD, van der Meulen J, Nauta JJ, Thijs LG. Acute renal failure in the medical intensive care unit: pre- disposing, complicating factors and outcome. Nephron. 1991;59(40):602-10.
Schwilk B, Wiedeck H, Stein B, Reinelt H, Treiber H, Bothner U. Epidemiology of acute renal failure and outcome of haemodiafiltration in intensive care. Intensive Care Med. 1997;23(12):1204-11.
Levy EM, Viscoli CM, Horwitz RI. The effect of acute renal failure on mortality. A cohort analysis. JAMA. 1996;275(19):1489-94.
Chertow GM, Lazarus JM, Paganini EP, Allgren RL, Lafayette RA, Sayegh MH. Predictors of mortality and the provision of dialysis in patients with acute tubular necrosis. The Auriculin Anaritide Acute Renal Failure Study Group. J Am Soc Nephrol. 1998;9(4):692-8.
Chertow GM, Christiansen CL, Cleary PD, Munro C, Lazarus JM. Prognostic stratification in critically ill patients with acute renal failure requiring dialysis. Arch Intern Med. 1995;155(14):1505-11.
Brivet FG, Kleinknecht DJ, Loirat P, Landais PJ. Acute renal failure in intensive care units – causes, outcome, and prognostic factors of hospital mortality: a prospective, multicenter study. French Study Group on Acute Renal Failure. Crit Care Med. 1996;24(2):192-8.
McWhirter JP, Pennington CR. Incidence and recognition of malnutrition in hospital. BMJ. 1994;308(6934):945-8.
Bistrian BR, Blackburn GL, Hallowell E, Heddle R. Protein status of general surgical patients. JAMA. 1974;230(6):858-60.
Owen WF, Lew NL, Liu Y, Lowrie EG, Lazarus JM. The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med. 1993;329(14):1001-6.
Abel RM, Beck CH, Abbott WM, Ryan JA, Barnett GO, Fischer JE. Improved survival from acute renal failure after treatment with intravenous essential L-amino acids and glucose. Results of a prospective, double-blind study. N Engl J Med. 1973;288(14):695-9.
Baek SM, Makabali GG, Bryan-Brown CW, Kusek J, Shoemaker WC. The influence of parenteral nutrition on the course of acute renal failure. Surg Gynecol Obstet. 1975;141(3):405-8.
McMurray SD, Luft FC, Maxwell DR, et al. Prevailing patterns and predictor variables in patients with acute tubular necrosis. Arch Intern Med. 1978;138(6):950-5.
Mirtallo JM, Schneider PJ, Mavko K, Ruberg RL, Fabri PJ. A comparison of essential and general amino acid infusions in the nutritional support of patients with compromised renal function. JPEN J Parenter Enteral Nutr. 1982;6(2):109-13.
Pelosi G, Proietti R, Arcangeli A, Magalini SI, Bondoli A. Total parenteral nutrition infusate. An approach to its optimal composition in post-trauma acute renal failure. Resuscitation. 1981;9(1):45-51.
Feinstein EI, Blumenkrantz MJ, Healy M, et al. Clinical and metabolic responses to parenteral nutrition in acute renal failure. A controlled double-blind study. Medicine (Baltimore). 1981;60(2):124-37.
Naylor CD, Detsky AS, O’Rourke K, Fonberg E. Does treatment with essential amino acids and hypertonic glucose improve survival in acute renal failure? A meta-analysis. Ren Fail. 1987-88;10(3-4):141-52.
Om P, Hohenegger M. Energy metabolism in acute uremic rats. Nephron. 1980;25(5):249-53.
Schneeweiss B, Graninger W, Stockenhuber F, et al. Energy metabolism in acute and chronic renal failure. Am J Clin Nutr. 1990;52(4):596-601.
Soop M, Forsberg E, Thörne A, Alvestrand A. Energy expen- diture in postoperative multiple organ failure with acute renal failure. Clin Nephrol. 1989;31(3):139-45.
Druml W. Nutritional support in acute renal failure. In: Hand- book of nutrition and kidney. Mitch WE, Klahr S, editors. Phila- delphia: Lippincott Williams & Wilkins; 2002. p. 191-213.
Druml W. Protein metabolism in acute renal failure. Miner Electrolyte Metab. 1998;24(1):47-54.
Clark AS, Mitch WE. Muscle protein turnover and glucose uptake in acutely uremic rats. Effects of insulin and the duration of renal insufficiency. J Clin Invest. 1983;72(3):836-45.
Kopple JD, Cianciaruso B, Massry SG. Does parathyroid hormone cause protein wasting? Contrib Nephrol. 1980;20:138-48.
Franz M, Hörl WH. Protein catabolism in acute renal failure. Miner Electrolyte Metab. 1997;23(3-6):189-93.
Ikizler TA, Flakoll PJ, Parker RA, Hakim RM. Amino acid and albumin losses during hemodialysis. Kidney Int. 1994;46(3):830-7.
Hynote ED, McCamish MA, Depner TA, Davis PA. Amino acid losses during hemodialysis: effects of high-solute flux and parenteral nutrition in acute renal failure. JPEN J Parenter Enteral Nutr. 1995;19(1):15-21.
Hakim RM. Clinical implications of hemodialysis membrane biocompatibility. Kidney Int. 1993;44(3):484-94.
Hakim RM, Wingard RL, Parker RA. Effect of the dialysis membrane in the treatment of patients with acute renal failure. N Engl J Med. 1994;331(20):1338-42.
Hakim RM, Breyer J, Ismail N, Schulman G. Effects of dose of dialysis on morbidity and mortality. Am J Kidney Dis. 1994;23(5):661-9.
Ikizler TA, Himmelfarb J. Nutrition in acute renal failure patients. Adv Ren Replace Ther. 1997;4(2 Suppl 1):54-63.
Luyckx VA, Bonventre JV. Dose of dialysis in acute renal failure. Semin Dial. 2004;17(1):30-6.
Friedlaender MM, Fervenza FC, Tsao T, Hsu F, Rabkin R. The insulin-like growth factor-I axis in acute renal failure. Ren Fail. 1998;20(2):343-8.
Boosalis MG, Ott L, Levine AS, et al. Relationship of visceral proteins to nutritional status in chronic and acute stress. Crit Care Med. 1989;17(8):741-7.
Daughaday WH, Rotwein P. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev. 1989;10(1):68-91.
Schwander JC, Hauri C, Zapf J, Froesch ER. Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status. Endocrinology. 1983;113(1):297-305.
Furlanetto RW, Underwood LE, Van Wyk JJ, D’Ercole AJ. Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay. J Clin Invest. 1977;60(3):648-57.
D’Ercole AJ, Stiles AD, Underwood LE. Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA.1984;81(3):935-9.
Holly JMP, Wass JA. Insulin-like growth factors; autocrine, paracrine or endocrine? New perspectives of the somatomedin hypothesis in the light of recent developments. J Endocrinol. 1989;122(30):611-8.
Copeland KC, Underwood LE, Van Wyk JJ. Induction of immu- noreactive somatomedin C human serum by growth hormone: dose-response relationships and effect on chromatographic profiles. J Clin Endocrinol Metab. 1980;50(4):690-7.
Thissen JP, Ketelslegers JM, Underwood LE. Nutritional regulation of the insulin-like growth factors. Endocr Rev. 1994;15(1):80-101.
Clemmons DR, Van Wyk JJ. Factors controlling blood concentrations of somatomedin C. Clin Endocrinol Metab. 1984;13(1):113-43.
Isley WL, Underwood LE, Clemmons DR. Dietary components that regulate serum somatomedin-C concentrations in humans. J Clin Invest. 1983;71(2):175-82.
Hawker FH, Stewart PM, Baxter RC, et al. Relationship of somatomedin-C/insulin-like growth factor I levels to conven- tional nutrition indices in critically ill patients. Crit Care Med. 1987;15(8):732-6.
Unterman TG, Vazquez RM, Slas AJ, Martyn PA, Phillips LS. Nutrition and somatomedin. XIII. Usefulness of somatomedin- C in nutritional assessment. Am J Med. 1985;78(2):228-34.
Donahue SP, Phillips LS. Response of IGF-1 to nutritional support in malnourished hospital patients: a possible indicator of short-term changes in nutritional status. Am J Clin Nutr. 1989;50(5):962-9.
Jacob V, Le Carpentier JE, Salzano S, et al. IGF-1, a marker of undernutrition in hemodialysis patients. Am J Clin Nutr. 1990;52(1):39-44.
Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999;340(6):448-54.
Phang PT, Aeberhardt LE. Effect of nutritional support on routine nutrition assessment parameters and body composition in intensive care unit patients. Can J Surg. 1996;39(3):212-9.
Culp K, Flanigan M, Lowrie EG, Lew N, Zimmerman B. Modeling mortality risk in hemodialysis patients using labora- tory values as time-dependent covariates. Am J Kidney Dis. 1996;28(5):741-6.
Herrmann FR, Safran C, Levkoff SE, Minaker KL. Serum albumin level on admission as a predictor of death, length of stay, and readmission. Arch Intern Med. 1992;152(1):125-30.
Church JM, Hill GL. Assessing the efficacy of intravenous nutrition in general surgical patients: dynamic nutritional as- sessment with plasma proteins. JPEN J Parenter Enteral Nutr. 1987;11(2):135-9.
Bernard MA, Jacobs DO, Rombeau JL. Suporte nutricional e metabólico de pacientes hospitalizados. In: Bernard MA, Jacobs DO, Rombeau JL, editores. Avaliação nutricional. Rio de Janeiro: Guanabara; 1988. p. 24-42.
Goldstein-Fuchs DJ. Assessment of nutritional status in renal diseases. In: Handbook of nutrition and kidney. Mitch WE, Klahr S, editors. Philadelphia: Lippincott Williams & Wilkins; 2002. p. 42-92.
Blackburn GL, Bistrian BR, Maini BS, Schlamm HT, Smith MF. Nutritional and metabolic assessment of the hospitalized patient. JPEN J Parenter Enteral Nutr. 1977;1(1):11-22.
Baker JP, Detsky AS, Wesson DE, et al. Nutritional assessment: a comparison of clinical judgement and objective measurements. N Engl J Med. 1982;306(16):969-72.
Detsky AS, McLaughlin JR, Baker JP, et al. What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr. 1987;11(1):8-13.
Kalantar-Zadeh K, Kleiner M, Dunne E, et al. Total iron-binding capacity-estimated transferrin correlates with the nutritional subjective global assessment in hemodialysis patients. Am J Kidney Dis. 1998;31(2):263-72.
Hasse J, Strong S, Gorman MA, Liepa G. Subjective global assessment: alternative nutrition-assessment technique for liver- transplant candidates. Nutrition. 1993;9(4):339-43.
Enia G, Sicuso C, Alati G, Zoccali C. Subjective global assess- ment of nutrition in dialysis patients. Nephrol Dial Transplant. 1993;8(10):1094-8.
Abdullah MS, Wild G, Jacob V, et al. Cytokines and the malnutrition of chronic renal failure. Miner Electrolyte Metab. 1997;23(3-6):237-42.
Adequacy of dialysis and nutrition in continuous peritoneal dialysis: association with clinical outcomes. Canada-USA (CA- NUSA). Peritoneal Dialysis Study Group. J Am Soc Nephrol. 1996;7(2):198-207.
Maiorca R, Cancarini GC, Brunori G, et al. Comparison of long-term survival between hemodialysis and peritoneal dialysis. Adv Perit Dial. 1996;12:79-88.
Maiorca R, Brunori G, Zubani R, et al. Predictive value of dialysis adequacy and nutritional indices for mortality and morbidity in CAPD and HD patients. A longitudinal study. Nephrol Dial Transplant. 1995;10(12):2295-305.
Fiaccadori E, Lombardi M, Leonardi S, Rotelli CF, Tortorella G, Borghetti A. Prevalence and clinical outcome associated with preexisting malnutrition in acute renal failure: a prospective cohort study. J Am Soc Nephrol. 1999;10(3):581-93.
Lowrie EG, Huang WH, Lew NL. Death risk predictors among peritoneal dialysis and hemodialysis patients: a preliminary comparison. Am J Kidney Dis. 1995;26(1):220-8.
Husebye DG, Westlie L, Styrvoky TJ, Kjellstrand CM. Psy- chological, social, and somatic prognostic indicators in old patients undergoing long-term dialysis. Arch Intern Med. 1987;147(11):1921-4.
Liu Y, Coresh J, Eustace JA, et al. Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition. JAMA. 2004;291(4):451-9.
Gordon BR, Parker TS, Levine DM, et al. Low lipid concentra- tions in critical illness: implications for preventing and treating endotoxemia. Crit Care Med. 1996;24(4):584-9.
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