Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants?
Palavras-chave:
Blood Glucose, Glycosuria, Hyperglycemia, Newborn Infant, Parenteral InfusionResumo
OBJETIVOS: Avaliar a ocorrência de glicosúria em recém-nascidos pré-termo submetidos à infusão parenteral de glicose e verificar a relação entre glicemia e glicosúria. METODOLOGIA: Foram realizadas 511 determinações concomitantes de glicemia e glicosúria em 40 recém-nascidos pré-termo recebendo infusão parenteral de glicose. Estes 511 pares foram dicotomizados conforme o “momento” clínico do recém-nascido no instante da coleta, em estáveis e instáveis, e estudados em relação à idade gestacional, peso de nascimento e velocidade de infusão de glicose. RESULTADOS: Os resultados revelaram maior frequência de glicosúria em idade gestacional £ 30semanas, peso de nascimento < 1500g e velocidade de infusão de glicose > 6mg/kg/min. Houve a ocorrência de 8 (25,8%) episódios de glicosúria positiva na ausência de hiperglicemia mostrando somente uma concordância moderada entre os dois fenômenos. CONCLUSÕES: A glicosúria não deve ser utilizada como indicadora de níveis glicêmicos nem de adequação da taxa da infusão de glicose. É necessário, portanto, a monitorização frequente da glicemia em recém-nascidos pré-termo submetidos à infusão de glicose.
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