Resultado da gravidez em mulheres aloimunes e com síndrome de antifosfolípide

um relato de caso

Autores

  • Serguei Abel Castañeda Ospina School of Medicine, Universidad de Antioquia
  • Wálter Darío Cardona Maya School of Medicine, Universidad de Antioquia
  • Julio César Bueno Sánchez School of Medicine, Universidad de Antioquia
  • Ángela Patricia Cadavid Jaramillo School of Medicine, Universidad de Antioquia

Palavras-chave:

Síndrome do anticorpo antifosfolípide, Aborto habitual, Heparina, Aspirina, Imunoterapia

Resumo

CONTEXTO: Mulheres com síndrome do anticorpo antifosfolípide e aloimunidade têm um mau prognóstico de gravidez. Existem muitas opções para o diagnóstico e o tratamento destas doenças, embora o tratamento mais adequado não esteja estabelecido. RELATO DE CASO: Apresentamos a evolução clínica e o tratamento de uma mulher com antecedentes de dois abortos e que vem sendo acompanhada, há 10 anos, em nosso serviço. Após o diagnóstico da síndrome do anticorpo antifosfolípide e de aloimunidade,, a paciente recebeu tratamento com heparina, aspirina e prednisona, além de imunizações com linfócitos. Nas duas gravidezes subseqüentes, teve dois bebês prematuros, que evoluíram com crescimento e desenvolvimento normais. A quinta gravidez não foi bem-sucedida, apesar de a paciente ter recebido um tratamento semelhante ao utilizado previamente embora após o início da gravidez, não planejada. Na discussão deste caso, enfatizamos os mecanismos patogênicos e o tratamento destas doenças.

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Biografia do Autor

Serguei Abel Castañeda Ospina, School of Medicine, Universidad de Antioquia

MD. Reproduction Program, School of Medicine, Universidad de Antioquia, Medellín, Colombia.

Wálter Darío Cardona Maya, School of Medicine, Universidad de Antioquia

MSc student. Reproduction Program, School of Medicine, Universidad de Antioquia, Medellín, Colombia.

Julio César Bueno Sánchez, School of Medicine, Universidad de Antioquia

MD. Reproduction Program, School of Medicine, Universidad de Antioquia, Medellín, Colombia.

Ángela Patricia Cadavid Jaramillo, School of Medicine, Universidad de Antioquia

MD, DSc. Reproduction Program, School of Medicine, Universidad de Antioquia, Medellín, Colombia.

Referências

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Cadavid A, Peña B, García G, et al. Heparin plus aspirin as a “single” therapy for recurrent spontaneous abortion associated with both allo- and autoimmunity. Am J Reprod Immunol 1999;41(4):271-8.

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Publicado

2003-11-11

Como Citar

1.
Ospina SAC, Maya WDC, Sánchez JCB, Jaramillo Ángela PC. Resultado da gravidez em mulheres aloimunes e com síndrome de antifosfolípide: um relato de caso. Sao Paulo Med J [Internet]. 11º de novembro de 2003 [citado 14º de março de 2025];121(6):248-50. Disponível em: https://periodicosapm.emnuvens.com.br/spmj/article/view/2647

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