SARS-CoV-2 and arbovirus infection

a rapid systematic review

Autores

Palavras-chave:

Severe acute respiratory syndrome coronavirus 2 [supplementary concept], Arbovirus infections, Coinfection, Syndemic, Prognosis

Resumo

BACKGROUND: The numbers of cases of arboviral diseases have increased in tropical and subtropical regions while the coronavirus disease (COVID-19) pandemic overwhelms healthcare systems worldwide. The clinical manifestations of arboviral diseases, especially dengue fever, can be very similar to COVID-19, and misdiagnoses are still a reality. In the meantime, outcomes for patients and healthcare systems in situations of possible syndemic have not yet been clarified. OBJECTIVE: We set out to conduct a systematic review to understand and summarize the evidence relating to clinical manifestations, disease severity and prognoses among patients coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and arboviruses. METHODS: We conducted a rapid systematic review with meta-analysis, on prospective and retrospective cohorts, case-control studies and case series of patients with confirmed diagnoses of SARS-CoV-2 and arboviral infection. We followed the Cochrane Handbook recommendations. We searched EMBASE, MEDLINE, Cochrane Library, LILACS, Scopus and Web of Science to identify published, ongoing and unpublished studies. We planned to extract data and assess the risk of bias and the certainty of evidence of the studies included, using the Quality in Prognosis Studies tool and the Grading of Recommendations Assessment. RESULTS: We were able to retrieve 2,407 citations using the search strategy, but none of the studies fulfilled the inclusion criteria. CONCLUSION: The clinical presentations, disease severity and prognoses of patients coinfected with SARS-CoV-2 and arboviruses remain unclear. Further prospective studies are necessary in order to provide useful information for clinical decision-making processes. PROTOCOL REGISTRATION NUMBER IN THE PROSPERO DATABASE: CRD42020183460

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Biografia do Autor

Keilla Martins Milby, Brazilian Cochrane Center

PhD. Nurse, Volunteer Researcher at Cochrane Brazil, São Paulo (SP), Brazil.

Alvaro Nagib Atallah, Brazilian Cochrane Center

MD, MSc, PhD. Nephrologist and Full Professor, Discipline of Emergency and Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil; Director, Cochrane Brazil, São Paulo (SP), Brazil.

César Ramos Rocha-Filho, Brazilian Cochrane Center

MSc. Biotechnologist and Doctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.

Ana Carolina Pereira Nunes Pinto, Brazilian Cochrane Center

MSc. Pharmacist and Doctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil; Volunteer Researcher, Cochrane Brazil, São Paulo (SP), Brazil.

Aline Pereira da Rocha, Brazilian Cochrane Center

MSc. Pharmacist and Doctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil; Volunteer Researcher, Cochrane Brazil, São Paulo (SP), Brazil.

Felipe Sebastião de Assis Reis, Brazilian Cochrane Center

MD, MPS. Manager, Medical Practices, Beneficência Portuguesa de São Paulo, São Paulo (SP), Brazi

Nelson Carvas Junior, Brazilian Cochrane Center

Physical Educator, Universidade Ibirapuera, São Paulo (SP), Brazil.

Vinicius Tassoni Civile, Brazilian Cochrane Center

MSc. Physiotherapist and Doctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil; Assistant Professor, Physiotherapy Course, Universidade Paulista (UNIP), São Paulo (SP), Brazil; Volunteer Researcher, Cochrane Brazil, São Paulo (SP), Brazil.

Rodolfo Rodrigo Pereira Santos, Universidade Federal de São Paulo

Statistician and Master’s Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil; Data Science Manager, Synova Health CRO, São Paulo (SP), Brazil.

Laura Jantsch Ferla, Brazilian Cochrane Center

Undergraduate Medical Student, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.

Giulia Fernandes Moça Trevisani, Brazilian Cochrane Center

Undergraduate Medical Student, Universidade Santo Amaro (UNISA), São Paulo (SP), Brazil.

Gabriel Sodré Ramalho, Brazilian Cochrane Center

Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.

Maria Eduarda dos Santos Puga, Brazilian Cochrane Center

MSc, PhD. Librarian, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.

Virgínia Fernandes Moça Trevisani, Brazilian Cochrane Center

MD, MSc, PhD. Rheumatologist, Discipline of Emergency and Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil; Rheumatologist, Discipline of Rheumatology, Universidade Santo Amaro (UNISA), São Paulo (SP), Brazil.

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Publicado

2020-12-03

Como Citar

1.
Milby KM, Atallah AN, Rocha-Filho CR, Pinto ACPN, Rocha AP da, Reis FS de A, Carvas Junior N, Civile VT, Santos RRP, Ferla LJ, Trevisani GFM, Ramalho GS, Puga ME dos S, Trevisani VFM. SARS-CoV-2 and arbovirus infection: a rapid systematic review. Sao Paulo Med J [Internet]. 3º de dezembro de 2020 [citado 14º de março de 2025];138(6):498-504. Disponível em: https://periodicosapm.emnuvens.com.br/spmj/article/view/566

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