A rare mediastinal occurrence of neuroblastoma in an adult

case report

Autores

Palavras-chave:

Mediastinum, Neuroblastoma, Adult

Resumo

CONTEXT: Neuroblastoma is the most common extracranial malignant solid tumor that occurs during childhood. It arises from primitive cells and is seen in the adrenal medulla and sympathetic ganglia of the sympathetic nervous system. CASE REPORT: We present a rare case of a 40-year-old man who was diagnosed with the onset of neuro-blastoma arising in the mediastinum. He was treated by means of surgical resection in the superior medi-astinum after neoadjuvant chemotherapy. The patient’s surgical outcome was satisfactory. CONCLUSION: There are still no standard treatment guidelines for adult neuroblastoma patients. Although they have a poor prognosis, the main treatment option should be complete surgery at an early stage. This situation may become clarified through biological and genetic studies in the future.

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Biografia do Autor

Fazli Yanik, Trakya Üniversitesi Tip Fakültesi

MD. Assistant Professor, Department of Thoracic Surgery, Trakya Üniversitesi Tip Fakültesi, Edirne, Turkey

Yekta Altemur Karamustafaoglu, Trakya Üniversitesi Tip Fakültesi

MD. Associate Professor, Department of Thoracic Surgery, Trakya Üniversitesi Tip Fakültesi, Edirne, Turkey

Yener Yoruk, Trakya Üniversitesi Tip Fakültesi

MD. Professor, Department of Thoracic Surgery, Trakya Üniversitesi Tip Fakültesi, Edirne, Turkey

Referências

Hallett A, Traunecker H. A review and update on neuroblastoma. Paediatrics and Child Health. 2012;22(3):103-7. Available from: http:// www.sciencedirect.com/science/article/pii/S1751722211001971. Accessed in 2017 (Aug 4).

Esiashvili N, Goodman M, Ward K, Marcus RB Jr, Johnstone PA. Neuroblastoma in adults: Incidence and survival analysis based on SEER data. Pediatr Blood Cancer. 2007;49(1):41-6.

Cohn SL, Pearson AD, London WB, et al. The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol. 2009;27(2):289-97.

Brodeur GM, Pritchard J, Berthold F, et al. Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol. 1993;11(8):1466-77.

Conter HJ, Gopalakrishnan V, Ravi V, et al. Adult versus Pediatric Neuroblastoma: The M.D. Anderson Cancer Center Experience. Sarcoma. 2014;2014:375151.

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Publicado

2019-02-07

Como Citar

1.
Yanik F, Karamustafaoglu YA, Yoruk Y. A rare mediastinal occurrence of neuroblastoma in an adult: case report. Sao Paulo Med J [Internet]. 7º de fevereiro de 2019 [citado 14º de março de 2025];137(1):104-6. Disponível em: https://periodicosapm.emnuvens.com.br/spmj/article/view/627

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