Maternal exposure to benzene and toluene and preterm birth

A longitudinal study

Autores

Palavras-chave:

Benzene, Toluene, Air pollutants, Child health, Prenatal care, Public policy

Resumo

BACKGROUND: Exposure to air pollutants has several effects on human health, including during pregnancy. OBJECTIVE: To identify whether exposure to benzene and toluene among pregnant women contributes to preterm delivery. DESIGN AND SETTING: Longitudinal study using data on newborns from mothers living in São José dos Campos (SP) in 2016, who had been exposed to benzene and toluene. METHODS: A logistic regression model with three hierarchical levels was constructed using maternal vari-ables relating to newborns, and using benzene and toluene concentrations in quartiles. Occurrences of cesarean births, twins or malformations were excluded. Maternal exposure windows of 5, 10, 15, 30, 60 and 90 days prior to delivery were considered. RESULTS: Out of the 9,562 live births, 3,671 newborns were included and 343 newborns were born at less than 37 weeks of gestation (9.3%). The average birth weight was 3,167.2 g. Exposure to benzene and toluene was significantly associated (P = 0.04) with preterm delivery in the five-day window. There was no association in any of the other exposure windows. CONCLUSIONS: It was possible to identify that maternal exposure to benzene and toluene has an acute effect on preterm delivery.

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Biografia do Autor

Djalma Antonio Almeida dos Santos, Universidade Estadual de São Paulo

MSc. Doctoral Student, Postgraduate Program on Mechanical Engineering, Department of Energy, Universidade Estadual de São Paulo (UNESP), Guaratinguetá, Brazil

Luiz Fernando Costa Nascimento, Universidade Estadual de São Paulo

MD, PhD. Researcher, Postgraduate Program on Mechanical Engineering, Department of Energy, Universidade Estadual de São Paulo (UNESP), Guaratinguetá, Brazil.

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Publicado

2019-12-05

Como Citar

1.
Santos DAA dos, Nascimento LFC. Maternal exposure to benzene and toluene and preterm birth: A longitudinal study. Sao Paulo Med J [Internet]. 5º de dezembro de 2019 [citado 29º de abril de 2025];137(6):486-90. Disponível em: https://periodicosapm.emnuvens.com.br/spmj/article/view/993

Edição

v. 137 n. 6 (2019)

Seção

Artigo Original

Licença

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.