The ACTH test in the diagnosis of hirsutism

Authors

  • Marco Fábio Prata Lima Federal University of São Paulo
  • Márcia Gaspar Nunes Federal University of São Paulo
  • Cláudio Emilio Bonduki Federal University of São Paulo
  • Mauro Abi Haidar Federal University of São Paulo
  • Geraldo Rodrigues Lima Federal University of São Paulo
  • Edmund Chada Baracat Federal University of São Paulo

Keywords:

ACTH, diagnosis, hirsutism, adrenal hyperplasia

Abstract

The ACTH test has been used to confirm the diagnosis of adrenal insufficiency and the classic and the non-classic adrenal hyperplasia due to the 3-HSD, 21 OH e 110H deficiencies. This article reviews the historical aspects of the use of ACTH in the diagnosis of hirsutism and points out its mains indications. In spite of new biological molecular advances in the diagnosis of adrenal enzymatic deficiencies, the use of the ACTH test can help the physician to predict both genothipus and fenothipus in populations with hyperandrogenic manifestations due to non-classical or late-onset congenital adrenal hyperplasia.

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Author Biographies

Marco Fábio Prata Lima, Federal University of São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina , Department of Gynecology, São Paulo, São Paulo, Brazil.

Márcia Gaspar Nunes, Federal University of São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Gynecology, São Paulo, São Paulo, Brazil.

Cláudio Emilio Bonduki, Federal University of São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Gynecology, São Paulo, São Paulo, Brazil.

Mauro Abi Haidar, Federal University of São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Gynecology, São Paulo, São Paulo, Brazil.

Geraldo Rodrigues Lima, Federal University of São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Gynecology, São Paulo, São Paulo, Brazil.

Edmund Chada Baracat, Federal University of São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Gynecology, São Paulo, São Paulo, Brazil.

References

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Published

1997-03-03

How to Cite

1.
Lima MFP, Nunes MG, Bonduki CE, Haidar MA, Lima GR, Baracat EC. The ACTH test in the diagnosis of hirsutism. Sao Paulo Med J [Internet]. 1997 Mar. 3 [cited 2025 Oct. 16];115(2):1403-5. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2094

Issue

Section

Review Article