Percutaneous transluminal angioplasty in the treatment of renovascular hypertension

sequential prospective study

Authors

  • Fausto Miranda Jr. Universidade Federal de São Paulo
  • Maria del Carmen Janeiro Perez Universidade Federal de São Paulo
  • Frida Plavnik Universidade Federal de São Paulo
  • João Francisco Jr. Universidade Federal de São Paulo
  • Emil Burihan Universidade Federal de São Paulo

Keywords:

Renovascular hypertension, Transluminal angioplasty, Renal artery stenosis, Atherosclerosis, Fibromuscular dysplasia

Abstract

OBJECTIVE: to evaluate the use of percutaneous transluminal renal angioplasty (PTRA) in the treatment of renal vascular hypertension. DESIGN: sequential prospective PTRA treatment of severe arterial hypertension, screening by the captopril test, confirmed by renal arteriography, and the result evaluated by post-PTRA arteriography, blood pressure measurement and renal function. SITE: Vascular Surgery, angioradiology sector, and Nephrology outpatients department of the Federal University of São Paulo - Paulista School of Medicine, São Paulo, Brazil, a tertiary health-care institution. PARTICIPANTS: PTRA was employed on 32 patients screened by clinical examination, captopril test and renal arteriography. EVALUATION: PTRA results were evaluated by the criteria of the Cooperative Study of Renovascular Hypertension. RESULTS: after PTRA the completion arteriography showed no renal stenosis in 24 patients (75%), residual stenosis (20-50%) in 3 (9.4%) and no change in 5 (15.6%). The blood pressure results were: 3 patients (9.4%) were cured, 24 (75%) improved: and 5 (15.6%) were unchanged. We observed normal renal function before and after PTRA in 25 patients (78%); altered pre- and improved post-PTRA in 2 (6.3%); post-PTRA remained unaltered in 2 (6.3%); and altered pre- and worsened post-PTRA in 3 (9.4%). Recurrence of stenosis occurred in one patient after 8 months. CONCLUSIONS: PTRA is a convenient procedure, relatively safe and an effective complementary method of medical therapy for controlling renovascular hypertension.

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Author Biographies

Fausto Miranda Jr., Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Medicine, São Paulo, São Paulo, Brazil.

Maria del Carmen Janeiro Perez, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Medicine, São Paulo, São Paulo, Brazil.

Frida Plavnik, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Medicine, São Paulo, São Paulo, Brazil.

João Francisco Jr., Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Medicine, São Paulo, São Paulo, Brazil.

Emil Burihan, Universidade Federal de São Paulo

Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Medicine, São Paulo, São Paulo, Brazil.

References

Gruntzig A, Kuhlmann U, Vetter W et al. Treatment of renovascular hypertension with percutaneous transluminar dilatation of a renal artery stenosis. Lancet 1978;1:801-802.

Grim CE, Luft FC, Yune HY et al. Percutaneous transluminar dilatation in the treatment of renal vascular hypertension. Ann. Intern. Med 1981; 95:439-442.

Katsen BT, Chang J, Lukowsky GH et al. Percutaneous transluminal angioplasty for treatment of renovascular hypertension. Radiology 1979;131:53-58.

Martin LG, Price RB, Casarella WJ et al. Percutaneous angioplasty in clinical management of renovascular hypertension: initial and long-term results. Radiology 1985;155:629-633.

Schwarten DE, Yune HY, Klatte EC et al. Clinical experience with percutaneous transluminal angioplasty (PTA) of stenotic arteries. Radiology 1980;135:601-604.

Schwarten DE. Transluminal angioplasty of renal artery stenosis: 70 experiences. AJR 1980;135:969-974.

Sos TA, Saddekni S, Sniderman KW et al. Renal artery angioplasty. Techniques and early results. Urol. Radiol. 1982;3:223-231.

Tegtmeyer CJ, Dyer R, Teates CD et al. Percutaneous transluminal dilatation of the renal arteries. Techniques and results. Radiology 1980;135:589-599.

Tegtmeyer CJ, Kotler TJ, Ayers CA. Renal angioplasty: current status. AJR 1984;142:17-21.

Zeitler E, Richter EJ, Roth FJ et al. Results of percutaneous transluminal angioplasty. Radiology 1983;146:57-60.

Becker GJ, Katzen BT, Dake MD. Noncoronary angioplasty. Radiology 1989;170:921-940.

Klinge J, Mali WPTM, Fuiglaert CBAJ et al. Percutaneous transluminal renal angioplasty: Initial and long-term results. Radiology 1989;171:501-506.

Boyer L, Bouchet F, Boissier A et al. Evolution de la créatininémie chez 140 patients hypertendus après succès technique de l'angioplastie transluminale percutanée de sténoses de l' ártère rénale. J.Radiol.1993;74:609-613.

Martin EC, Mattern RF, Baer L et al. Renal angioplasty for hypertension: predictive factors for long-term success. AJR 1981;137:921-924.

Tegtmeyer CJ, Kellum CD, Ayers C. Percutaneous transluminal angioplasty of the renal artery. Results and long-term follow-up. Radiology 1984;153:77-84.

Mahler F, Probst P, Haertel M et al. Last improvement of renovascular hypertension by transluminal dilatation of atherosclerotic and nonatherosclerotic renal artery stenosis. A follow-up study. Circulation 1982;65:611-617.

Colapinto RF, Stronell RD, Harries-Jones EP et al. Percutaneous transluminal dilatation of the renal artery: follow-up studies on renovascular hypertension. AJR 1982; 139:727-732.

Silva HB, Frimm CC, Bortolotto LA et al. Angioplastia percutânea e revascularização cirúrgica em hipertensão renovascular. Experiência no tratamento e seguimento de longo prazo em 124 pacientes. Arq Bras Cardiol 1994; 62:417-423.

Casalini E, Sfondrini MS, Fossali E. Two-year clinical follow-up of children and adolescents after percutaneous transluminal angioplasty for renovascular hypertension. Invest Radiol 1995;30:40-43.

Von Knorring J, Edgren J, Lepäntalo M. Long-term results of percutaneous transluminal angioplasty in renovascular hypertension. Acta Radiol 1996;37:36-40.

Libertino JÁ, Beckmann CF. Surgery and percutaneous angioplasty in the management of renovascular hypertension. Urol Clin North Am 1994;21:235-243.

Xicai C, Enhui W, Jiwu C et al. Experimental renal artery stenosis and angioplasty. The mechanism of the angioplasty. Chin Med J (Engl) 1995;108:113-116.

Tedeschi AL, Peixoto ECS, Rachid MBF et al. Angioplastia renal transluminal percutânea no tratamento da hipertensão renovascular. Arq. Bras. Cardiol 1993;60:327-333.

Raynaud A, Lucino S, Almeida Augusto MC et al. Angioplastie endoluminale percutenée des reins transplantés. Suivi à long terme. J Radiol 1994;75:81-86.

Cluzel P, Raynaud A, Beyssen B et al. Stenoses of renal branch arteries in fibromuscular dysplasia: results of percutaneous transluminal angioplasty. Radiology 1994; 193:227-232.

Hoffman O, Raynaud A, Tsocanakis O et al. Sténoses ostiales des artères rénales: traitement par angioplastie. J Mal Vasc 1994;19(suppl A):90-91.

Eldrup-Jorgensen J, Harvey HR, Sampson LN et al. Should percutaneous transluminal renal artery angioplasty be applied to ostial renal artery atherosclerosis? J Vasc Surg 1995;21:909-914.

Lasry JL, Qanadli S, Lafitte F et al. Occlusion de l'artère rénale: revascularisation percutanée. J Mal Vasc 1994; 19(suppl A):129-135.

Sos TA, Pickering TG, Sniderman K et al. Percutaneous transluminal renal angioplasty in renovascular hypertension due to atheroma or fibromuscular dysplasia. N Engl J Med 1983;309:274-279.

Sos TA, Saddekni S, Pickering TG et al. Technical aspects of percutaneous transluminal angioplasty in renovascular disease. Nephron 1986;44(suppl 1):45-50.

Srur MF, Sos TA, Saddekni S et al. Intimal fibromuscular dysplasia and Takayasu arteritis: delayed response to percutaneous transluminal renal angioplasty. Radiology 1985;157:657-660.

Tegtmeyer CJ, Sos TA. Techniques of renal angioplasty. Radiology 1986;161:577-586.

Maxwell MH, Bleifer KH, Franklin SS et al. Cooperative study of renovascular hypertension. Demographic analysis of the study. JAMA 1972;220:1195-1204.

Madias NE, Kwon OJ, Millan VG. Percutaneous transluminal renal angioplasty: a potentially effective treatment for preservation of renal function. Arch Intern Med 1982;142:693-697.

Luscher TF, Keller HM, Imhof HG et al. Fibromuscular hyperplasia: extension of the disease and therapeutic outcome. Results of the University Hospital Zurich Cooperative study of fibromuscular hyperplasia. Nephron 1986;44(suppl 1):109-114.

Milian VG, Most WE, Madias NE. Nonsurgical treatment of severe hypertension due to renal artery intimal fibroplasia by percutaneous transluminal angioplasty. N Engl J Med 1979;30:1371-1373.

Saddekni S, Sniderman KW, Hilton S et al. Percutaneous transluminal angioplasty of nonatherosclerotic lesions. AJR 1980;135:975-982.

Tegtmeyer CJ, Elson J, Glass TA et al. Percutaneous transluminal angioplasty: the treatment of choice for renovascular hypertension due to fibromuscular dysplasia. Radiology 1982;143:631-637.

Cicuto KP, McLean GK, Oleaga JA et al. Renal artery stenosis: anatomic classification for percutaneous transluminal angioplasty. AJR 1981;137:599-601.

Grim CE, Yune HY, Donahue JP et al. Renal vascular hypertension. Nephron 1986; 44(suppl 1):96-100.

Buist T. Percutaneous renal angioplasty. J.R. Soc Med 1985; 78:353-354.

Rees CR, Palmaz JC, Becker GJ et al. Palmaz stent in atherosclerotic stenosis involving the ostia of the renal arteries: preliminary report of a multicentric study. Radiology 1991;181:507-514.

Espinosa G, Mariz A, Murad H. Angioplastia e implante primário de prótese endoluminar de Palmaz no tratamento da estenose proximal da artéria renal: resultados preliminares. Cir Vasc Angiol 1996;12:171-179.

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Published

1998-01-01

How to Cite

1.
Miranda Jr. F, Perez M del CJ, Plavnik F, Francisco Jr. J, Burihan E. Percutaneous transluminal angioplasty in the treatment of renovascular hypertension: sequential prospective study. Sao Paulo Med J [Internet]. 1998 Jan. 1 [cited 2025 Oct. 16];116(1):1613-7. Available from: https://periodicosapm.emnuvens.com.br/spmj/article/view/2249

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